Styrenes
Selleck Chemical LLC CPI-637
CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor with IC50 values of 0 03 M and 0 051 M for CBP and EP300 respectively in TR-FRET assay It is highly selective against other bromodomains displaying substantial biochemical activity only against BRD9
Selleck Chemical LLC NMS-873
NMS-873 is an allosteric and specific p97 inhibitor with IC50 of 30 nM that demonstrates potent selectivity for VCP/p97 compared to a panel of other AAA ATPases Hsp90 and 53 additional analyzed kinases (IC50s 10 M)
Sigma Aldrich Fine Chemicals Biosciences Methyl isoeugenol >=98%, FG | 93-16-3 | MFCD00009282 | 250G
Methyl isoeugenol >=98%, FG | Purity: >=98% | Mol Wt: 178.23 | 93-16-3 | MFCD00009282 | 250G
Chemscene ChemScene | β-Bromostyrene | 500G | CS-0059292 | 0.97 | 103-64-0| MFCD00000185 | 183.048
ChemScene | β-Bromostyrene | 500G | CS-0059292 | 0.97 | 103-64-0| MFCD00000185 | 183.048
Chemscene ChemScene | (E)-1-Bromo-4-(2-nitrovinyl)benzene | 5G | CS-W016767 | 0.98 | 5153-71-9| MFCD00191856 | 228.04
ChemScene | (E)-1-Bromo-4-(2-nitrovinyl)benzene | 5G | CS-W016767 | 0.98 | 5153-71-9| MFCD00191856 | 228.04
Sigma Aldrich Fine Chemicals Biosciences Combretastatin A4 >=98% (HPLC), powder | 117048-59-6 | MFCD03453309 | 5MG
Combretastatin A4 >=98% (HPLC), powder | Purity: >=98% (HPLC) | Mol Wt: 316.35 | 117048-59-6 | MFCD03453309 | 5MG
Chemscene ChemScene | (E)-1-Bromo-4-(2-nitrovinyl)benzene | 10G | CS-W016767 | 0.98 | 5153-71-9| MFCD00191856 | 228.04
ChemScene | (E)-1-Bromo-4-(2-nitrovinyl)benzene | 10G | CS-W016767 | 0.98 | 5153-71-9| MFCD00191856 | 228.04
Medchemexpress LLC CPI-637 | 1884712-47-3 | MFCD30489741 | 99.9% | 386.45 g/mol | C22H22N6O | 10 MG
CPI-637 is a selective, cell-active CBP/EP300 bromodomain inhibitor used in epigenetic and cancer biology research. It demonstrates low-nanomolar biochemical potency against CBP and EP300 and shows cellular activity in the submicromolar range.
- Selective inhibition of CBP and EP300 bromodomains (IC50 = 0.03 μM and 0.051 μM).
- Reduced activity against BRD4 BD1 (IC50 = 11.0 μM).
- Cellular activity with CBP BRET EC50 ≈ 0.3 μM.
- High reported purity (~99.9%) suitable for research applications.
- Chemical formula C22H22N6O; molecular weight 386.45 g·mol⁻¹.
![Sigma Aldrich Fine Chemicals Biosciences (RP)-1-[(R)-alpha-(Dimethylamino)-2-(diphenylphosphino)benzyl]-2-diphenylphosphinoferrocene optical purity ee: >=99% | 1003012-96-1 | 100MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/501861629.PNG-250.jpg)
Sigma Aldrich Fine Chemicals Biosciences (RP)-1-[(R)-alpha-(Dimethylamino)-2-(diphenylphosphino)benzyl]-2-diphenylphosphinoferrocene optical purity ee: >=99% | 1003012-96-1 | 100MG
(RP)-1-[(R)-alpha-(Dimethylamino)-2-(diphenylphosphino)benzyl]-2-diphenylphosphinoferrocene optical purity ee: >=99% | Mol Wt: 687.57 | 1003012-96-1 | 100MG
![eMolecules 62566-68-1 | (-)-(R)-4-BROMOSTYRENE OXIDE IN HEXANE (1:1 W/W) | AstaTech | MFCD08277298 | 199.047 | C8H7BrO | 95.000 | Brc1ccc(cc1)[C@@H]1CO1 | 1g | 112523457](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502171622.JPG-250.jpg)
eMolecules 62566-68-1 | (-)-(R)-4-BROMOSTYRENE OXIDE IN HEXANE (1:1 W/W) | AstaTech | MFCD08277298 | 199.047 | C8H7BrO | 95.000 | Brc1ccc(cc1)[C@@H]1CO1 | 1g | 112523457
(-)-(R)-4-BROMOSTYRENE OXIDE IN HEXANE (1:1 W/W) | AstaTech | 62566-68-1 | MFCD08277298 | 199.047 | C8H7BrO | 95.000 | Brc1ccc(cc1)[C@@H]1CO1 | 1g | 112523457
Chem-Impex International, Inc. Tris(dibenzylideneacetone)dipalladium (0)-chloroform adduct | 52522-40-4 | MFCD00075479 | 25G
Tris(dibenzylideneacetone)dipalladium (0)-chloroform adduct, 52522-40-4, MFCD00075479, 25G
Matrix Scientific TRIS(DIBENZYLIDENEACETONE)DI-1
Tris(dibenzylideneacetone)dipalladium-chloroform Adduct Mf C52h43cl3o3pd2 Mw 1035.08 Cas 52522-40-4 Mdl MFCD00075479
Medchemexpress LLC N-(4-benzyl-3-methyl-1,2,4-thiadiazol-5-ylidene)-N'-phenylbenzenecarboximidamide | 324579-65-9 | 99.9% | 384.50 g/mol | C23H20N4S | 10MM 1ML
RNF5 inhibitor inh-02 is a small-molecule inhibitor of the E3 ubiquitin ligase RNF5 used in research to rescue F508del-CFTR function and to study autophagy and ubiquitin-mediated proteostasis. The compound has molecular formula C23H20N4S, exact mass 384.50 g/mol, and is typically provided as a 10 mM solution in DMSO or as solid quantities for assay and synthesis work.
- Potent inhibitor of E3 ubiquitin ligase RNF5 with cell-based activity (EC50 ≈ 2.2-2.6 μM).
- Available as 10 mM solution in DMSO and as multiple solid pack sizes.
- High purity (99.9%).
- Recommended solvent for solution preparation: DMSO.
- Storage: powder -20°C (up to 3 years); in solvent -80°C (6 months) or -20°C (1 month).
- Suitable for cystic fibrosis research and studies of protein quality control and autophagy.
Medchemexpress LLC Omega-3 arachidonic acid ethyl ester | 123940-93-2 | 98.0% | 332.52 | C22H36O2 | 1MG
Omega-3 arachidonic acid ethyl ester is the ethyl-ester derivative of an omega-3 polyunsaturated fatty acid supplied in ethanol at high purity. It provides increased lipophilicity compared with the free acid and is intended for lipid research, formulation, and analytical applications. Molecular formula C22H36O2; molecular weight 332.52 g/mol. Available in small vial sizes suitable for analytical and preparative use.
- Supplied in ethanol at 98.0% purity.
- Ethyl ester increases lipophilicity for formulation and metabolism studies.
- Suitable for analytical and preparative lipid research.
- Molecular formula C22H36O2; molecular weight 332.52 g/mol.
- Available in small vial sizes for laboratory use.