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Organic compounds that contain a sulfonanilide group; this functional group is a type of sulfonamide consisting of a sulfur atom bonded to two oxygen atoms via double bonds, one carbon atom, and one nitrogen atom; they are derivatives of aniline.
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(R)-BAY-899 is the R-enantiomer of BAY-899, an orally active and selective luteinizing hormone receptor (LH-R) antagonist. It exhibits IC50s of 185 nM for human LH and 46 nM for rat LH.
Selective luteinizing hormone receptor antagonist
Orally active
IC50s: 185 nM for hLH, 46 nM for rLH
Molecular weight: 459.45
Chemical formula: C25H19F2N5O2
Appearance: Off-white to light yellow solid
Storage as powder: -20°C for 3 years, 4°C for 2 years
Storage in solvent: -80°C for 6 months, -20°C for 1 month
Solubility in DMSO: 125 mg/mL (272.06 mM)
Solubility (in vivo): ≥ 5 mg/mL in various protocols
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