Sulfanylbenzoic acids and derivatives
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Medchemexpress LLC 2-methylthio-ATP tetrasodium | 100020-57-3 | 98.0% | 641.20 g/mol | C11H14N5Na4O13P3S | 1 MG
2-Methylthio-ATP tetrasodium is the tetrasodium salt of the ATP analogue 2-methylthio-ATP. It is used in pharmacological and receptor-binding studies to activate P2X and P2Y purinergic receptors and to probe platelet aggregation pathways.
- Acts as non-specific P2 receptor agonist.
- Causes noncompetitive inhibition of ADP-induced human platelet aggregation.
- Tetrasodium salt with high water solubility (H2O: 50 mg/mL).
- High purity (98.0%) for consistent experimental results.
- Stable as a sealed solid at -20°C; solutions stable at -80°C up to 6 months.
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Medchemexpress LLC Synstatin (92-119) | 1259384-47-8 | 99.4% | 3032.27 | 10 MG
Synstatin (92-119) is a synthetic peptide that acts as an inhibitor of αvβ3/αvβ5 integrins and IGF1R, exhibiting anti-angiogenic, anti-proliferative, antioxidant, and anti-tumor activities. It competitively blocks the capture of αvβ3/αvβ5 integrins and IGF1R by syndecan-1, disrupting the formation of the syndecan-1 : integrin : IGF1R ternary complex and inhibiting integrin activation. This compound is delivered as a white to off-white solid, readily soluble in DMSO and H2O.
- Inhibitor of αvβ3/αvβ5 integrins and IGF1R
- Exhibits anti-angiogenic, anti-proliferative, antioxidant, and anti-tumor effects
- Disrupts syndecan-1:integrin:IGF1R ternary complex formation
- Inhibits integrin activation and talin-mediated signaling pathways
- Blocks VEGF-induced angiogenesis
- White to off-white solid appearance
- Soluble in DMSO and H2O