Tosyl compounds
Medchemexpress LLC Lansoprazole sulfone | 131926-99-3 | 99.52% | 385.36 | 25 MG
Lansoprazole sulfone (AG-1813) is an orally active and selective inhibitor of H+, K+-ATPase. It significantly stimulates gastric acid secretion by inhibiting H+, K+-ATPase. This product has potential applications in treating duodenal ulcer, gastric ulcer, gastroesophageal reflux disease, and Zollinger-Ellison disease. It is for research use only and not sold to patients.
- Orally active and selective H+, K+-ATPase inhibitor.
- Significantly stimulates gastric acid secretion by inhibiting H+, K+-ATPase.
- Potential applications in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease, and Zollinger-Ellison disease.
Medchemexpress LLC o-Tolyl-isocyanate-d7 | 1219802-73-9 | C8D7NO | 25 MG
o-Tolyl-Isocyanate-d7 is the deuterium labeled o-Tolyl-Isocyanate. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Contains stable heavy isotopes of hydrogen, carbon, and other elements
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC 4-(3-tosyl-2-(tosylmethyl)propanoyl)benzoic acid | 124243-00-1 | MFCD28142486 | >97.0% | 500.58 g/mol | C25H24O7S2 | 50 MG
4-(3-tosyl-2-(tosylmethyl)propanoyl)benzoic acid is a tosylated benzoic-acid derivative used as a research chemical and biochemical assay reagent. It contains a free carboxylic acid and two tosyl groups and is typically supplied in small milligram quantities for synthetic and assay applications.
- Contains two tosyl groups and a free carboxylic acid.
- Used as a biochemical assay reagent and synthetic intermediate.
- Typical purity around 97% (batch-dependent).
- Molecular weight 500.58 g/mol; chemical formula C25H24O7S2.
- Available in small milligram pack sizes for research use.
TARGETMOL CHEMICALS INC Lansoprazole sulfone 5MG
Also available in 1 mL, 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Lansoprazole sulfone is a metabolite of the gastric pump inhibitor Lansoprazole. Purity 100%
Medchemexpress LLC Sultamicillin tosylate | 83105-70-8 | 1 ML
Sultamicillin tosylate is a broad-spectrum and orally active beta-lactamase inhibitor, and an antibiotic with antibacterial activity. It is for research use only.
- Acts as a broad-spectrum and orally active beta-lactamase inhibitor.
- Exhibits antibacterial activity.
- Shows activity against MRSA with a MIC value of 25 μg/mL in vitro.
- Hydrolyzes to Sulbactam and Ampicillin upon oral absorption.
- Improves survival in experimental polymicrobial sepsis models in mice.
- Enhances bacterial clearance when combined with immunosuppression agents.
- Storage (solid): 4°C, sealed, away from moisture and light.
- Storage (in solvent): -80°C for 6 months; -20°C for 1 month, sealed, away from moisture and light.
Medchemexpress LLC Toltrazuril (sulfone) | 69004-04-2 | 98.6% | 457.38 | 1 ML
Toltrazuril sulfone (Ponazuril) is a metabolite of Toltrazuril that exhibits antiprotozoal activity. This triazine anticoccidial agent was developed to prevent coccidiosis in poultry. It has been shown to inhibit the development of merozoites in S. neurona and N. caninum, and it also prevents the replication of T. gondii.
- Exhibits antiprotozoal activity.
- Developed as a triazine anticoccidial for poultry.
- Inhibits development of merozoites in S. neurona.
- Inhibits development of N. caninum.
- Prevents T. gondii replication.
- Effective in preventing and treating toxoplasmosis in mice.
Medchemexpress LLC Toltrazuril (sulfone) | 69004-04-2 | 98.6% | 457.38 | 500 MG
Toltrazuril sulfone (Ponazuril) is a metabolite of Toltrazuril, possessing antiprotozoal activity. It is a triazine anticoccidial developed to prevent coccidiosis in poultry.
- Inhibits the development of merozoites of *S. neurona*.
- It inhibits the development of *N. caninum* approximately 48 hours post-exposure.
- It exhibits inhibitory effects possibly by targeting different enzyme/enzyme systems in various apicomplexans.
- Inhibits *T. gondii* replication after the second division by endodyogeny (5 mg/ml; 20 hours).
- Effective in preventing and treating toxoplasmosis in mice (10-20 mg/kg; p.o.; daily; for 10 days).
Medchemexpress LLC Toltrazuril (sulfone) | 69004-04-2 | 98.6% | 457.38 | 1 G
Toltrazuril sulfone (Ponazuril) is a metabolite of Toltrazuril that exhibits antiprotozoal activity. It is a triazine anticoccidial developed for the prevention of coccidiosis in poultry. The product is for research use only and not for sale to patients.
- Antiprotozoal activity.
- Metabolite of Toltrazuril.
- Triazine anticoccidial.
- Developed to prevent coccidiosis in poultry.
- Inhibits the development of merozoites of *S. neurona* *in vitro*.
- Inhibits the development of *N. caninum* *in vitro* after approximately 48 hours post-exposure.
- Exhibits inhibitory effects possibly by targeting different enzyme/enzyme systems in various apicomplexans.
- Inhibits *T. gondii* replication *in vitro* after the second division by endodyogeny.
- Effective *in vivo* in preventing and treating toxoplasmosis in mice at dosages of 10-20 mg/kg (p.o.; daily; for 10 days).
Selleck Chemical LLC BAY 11-7082 50mg 19542-67-7 BAY 11-7821
BAY 11-7082 (BAY 11-7821) is a NF-?B inhibitor, inhibits TNF?-induced I?B? phosphorylation with IC50 of 10 ?M in tumor cells. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 with IC50 of 0.19 ?M and 0.96 ?M, respectively. BAY 11-7082 induces apoptosis and S phase arrest in gastric cancer cells. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC 4-(3-tosyl-2-(tosylmethyl)propanoyl)benzoic acid | 124243-00-1 | MFCD28142486 | >97.0% | 500.58 g/mol | C25H24O7S2 | 10 MG
4-(3-tosyl-2-(tosylmethyl)propanoyl)benzoic acid is a benzoic acid derivative supplied as a research reagent for biochemical assays and chemical synthesis. It has the molecular formula C25H24O7S2 and a molecular weight of 500.58 g/mol, and is provided as a solid for laboratory use.
- Benzoic acid derivative used as a biochemical assay reagent.
- CAS number 124243-00-1.
- Molecular weight 500.58 g/mol; formula C25H24O7S2.
- Purity greater than 97.0% as reported by third-party suppliers.
- Storage: store at room temperature for up to 3 years; in solvent, keep at -80°C for 2 years or -20°C for 1 year.
Medchemexpress LLC Rabeprazole sulfone | 117976-47-3 | MFCD08063743 | 250mg
Rabeprazole sulfone is a metabolite of the proton pump inhibitor Rabeprazole and is an impurity reference for Rabeprazole[1]
Sigma Aldrich Fine Chemicals Biosciences Bay 11-7082 >=98% (HPLC), powder | 19542-67-7 | MFCD00712162 | 10MG
Bay 11-7082 >=98% (HPLC), powder | Purity: >=98% (HPLC) | Mol Wt: 207.25 | 19542-67-7 | MFCD00712162 | 10MG
