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Filtered Search Results
Medchemexpress LLC Protac BCR-ABL1 ligand 1 | 2489876-34-6 | 99.2% | 347.29 g/mol | C17H12F3N3O2 | 5 MG
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PROTAC BCR-ABL1 ligand 1 is a small-molecule PROTAC ligand (GMB-475) that allosterically binds BCR-ABL1 and recruits the Von Hippel-Lindau (VHL) E3 ligase to promote ubiquitination and proteasomal degradation. Supplied for research use as a solid, it is provided at high purity for biochemical and cell-based studies.
- Allosteric ligand for BCR-ABL1 that promotes target degradation.
- Recruits VHL E3 ligase to facilitate ubiquitination.
- High purity suitable for biochemical and cell-based assays.
- Molecular weight 347.29 g/mol, compatible with screening workflows.
- Available in small research quantities for screening and validation.
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Cambridge Isotope Laboratories JECS Labeled Mixture Solution in water (ultrapure) 1 2 mL
JECS Labeled Mixture Solution in water (ultrapure) 1 2 mL
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BIOHIPPO AAV-hSyn-CaMPARI2-WPRE-pA
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Recombinant adeno associated virus expressing CaMPARI2 under the hSyn promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
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Medchemexpress LLC 2-methylbutanal | 96-17-3 | MFCD00006984 | 98.6% | 86.13 g/mol | C5H10O | 100 G
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2-Methylbutanal (2-methylbutyraldehyde) is a volatile aliphatic aldehyde supplied for laboratory research and analytical use. It is reported as a biomarker for detection of the uropathogen Proteus and is provided as a liquid reagent with reported high purity suitable for chromatographic and biochemical applications.
- Volatile aldehyde used as an analytical standard.
- Reported biomarker for detection of Proteus species.
- High reported purity (98.56%).
- Liquid physical state; density approximately 0.8131 g/cm³.
- Suitable for chromatographic and analytical workflows.
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Medchemexpress LLC HDAC-IN-27 dihydrochloride | 3069831-25-7 | ≥99.0% | C20H24Cl2N4O2 | 10MG
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HDAC-IN-27 dihydrochloride is a potent, class I-selective histone deacetylase (HDAC) inhibitor provided as the dihydrochloride salt for research use. It exhibits low-nanomolar inhibition of HDAC1-3, shows both in vitro and in vivo antitumor activity, and promotes histone acetylation and apoptosis in cancer cell models. The material is supplied as a high-purity solid for biochemical and cellular assays.
- Potent class I HDAC inhibitor with low-nanomolar activity.
- Demonstrated in vitro and in vivo antitumor activity.
- Induces apoptosis and histone acetylation in cell studies.
- Supplied as a dihydrochloride salt suitable for handling and formulation.
- High purity (≥99.0%) appropriate for research assays.
- Storage: 4°C sealed; in solution keep at -80°C for long-term storage.
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![Medchemexpress LLC 7-methyl-5-[3-(piperazin-1-ylmethyl)-1,2,4-oxadiazol-5-yl]-2-[[4-(trifluoromethoxy)phenyl]methyl]-3H-isoindol-1-... | 1092453-15-0 | MFCD31657360 | 98.0% | 487.47 g/mol | C24H24F3N5O3 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000239748.png-250.jpg)
Medchemexpress LLC 7-methyl-5-[3-(piperazin-1-ylmethyl)-1,2,4-oxadiazol-5-yl]-2-[[4-(trifluoromethoxy)phenyl]methyl]-3H-isoindol-1-... | 1092453-15-0 | MFCD31657360 | 98.0% | 487.47 g/mol | C24H24F3N5O3 | 25 MG
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AZD-8529 is a research-stage small-molecule positive allosteric modulator (PAM) of the metabotropic glutamate receptor 2 (mGluR2). It is used in preclinical pharmacology and behavioral studies to probe mGluR2-mediated signaling and pharmacodynamics. Supplied as a high-purity solid for laboratory research.
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eMolecules Pharmablock 7-bromo-2-chloroquinazoline 25mg 551066785 PB02878 0 000 953039-66-2 MFCD11040175 243 490 C8H4BrClN2
Pharmablock 7-bromo-2-chloroquinazoline 25mg 551066785 PB02878 0 000 953039-66-2 MFCD11040175 243 490 C8H4BrClN2
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![eMolecules Ambeed / Sodium (4aR6R7R7aR)-6-(6-butyramido-9H-purin-9-yl)-7-(butyryloxy)tetrahydro-4H-furo[32-d][132]dioxaphosphinin-2-olate 2-oxide / 1mg / 699858722 / A976872 / / 16980-89-5 / MFCD00005843 / 491.373 / C18H23N5NaO8P](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502425927.JPG-250.jpg)
eMolecules Ambeed / Sodium (4aR6R7R7aR)-6-(6-butyramido-9H-purin-9-yl)-7-(butyryloxy)tetrahydro-4H-furo[32-d][132]dioxaphosphinin-2-olate 2-oxide / 1mg / 699858722 / A976872 / / 16980-89-5 / MFCD00005843 / 491.373 / C18H23N5NaO8P
Ambeed / Sodium (4aR6R7R7aR)-6-(6-butyramido-9H-purin-9-yl)-7-(butyryloxy)tetrahydro-4H-furo[32-d][132]dioxaphosphinin-2-olate 2-oxide / 1mg / 699858722 / A976872 / / 16980-89-5 / MFCD00005843 / 491.373 / C18H23N5NaO8P
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Apexbio Technology LLC Clodronate Liposomes(Synonyms: Clodronate Liposome, Liposomal Clodronate, Clodronate-encapsulated Liposomes), 5mL.
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Clodronate Liposomes are lipid-based formulations containing encapsulated sodium clodronate designed as macrophage depletion agents for biomedical research Once phagocytosed by macrophages the liposomes release clodronate intracellularly upon lysosomal phospholipase digestion inducing macrophage apoptosis selectively In animal models intravenous administration achieves substantial macrophage depletion in spleen tissue within 24 hours post-injection Researchers employ Clodronate Liposomes to study macrophage functions and related immune-mediated pathologies utilizing various routes such as intravenous intraperitoneal subcutaneous intranasal or direct organ injection
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Medchemexpress LLC AMCA-X SE | 216309-02-3 | ≥97.0% | 443.45 | 1 MG
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AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm.
- Generates fixed blue fluorescence
- Forms stable amide bonds with primary amine groups
- Used as a reactive dye for labeling amino groups
- Suitable for peptides, proteins, and oligonucleotides
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Medchemexpress LLC Cinchophen | 132-60-5 | 99.9% | 25 G
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Cinchophen is a potent and orally active non-steroidal anti-inflammatory agent that exhibits analgesic and antimicrobial effects. This compound is utilized in research for conditions such as arthritis and various liver diseases.
- Potent and orally active non-steroidal anti-inflammatory agent
- Exhibits analgesic effects
- Possesses antimicrobial properties
- Used in research for arthritis and liver diseases
- Targets bacterial and anti-infection pathways
- Appears as a white to off-white solid
- For research use only
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Medchemexpress LLC Busulfan | 55-98-1 | 99.9% | 25 G
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Busulfan is a potent alkylating antineoplastic agent that causes DNA damage by cross-linking DNAs and DNA and proteins. It inhibits thioredoxin reductase and induces apoptosis, functioning as an immunosuppressive and myeloablative chemotherapeutic agent. This product is intended for research and analytical applications.
- Causes DNA damage by cross-linking DNAs and DNA and proteins
- Inhibits thioredoxin reductase
- Induces apoptosis
- Functions as an immunosuppressive and myeloablative chemotherapeutic agent
- Targets DNA alkylator/crosslinker, apoptosis, and various diseases
- Used to induce aplastic anemia models in research
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Medchemexpress LLC Taurine | 107-35-7 | 99.9% | 100 G
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Taurine is a sulfur-containing amino acid and an organic osmolyte involved in cell volume regulation. It provides a substrate for the formation of bile salts and plays a role in modulating intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes.
- Involved in cell volume regulation
- Provides a substrate for bile salt formation
- Modulates intracellular free calcium concentration
- Activates autophagy in adipocytes
- One of the most abundant amino acids in the brain and spinal cord, leukocytes, heart, muscle cells, and retina
- Exhibits diverse biological actions including protection against ischemia-reperfusion injury
- Offers antioxidant, antiatherogenic, and blood pressure-lowering effects
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Medchemexpress LLC Riboflavin | 83-88-5 | 99.89% | 25 G
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Riboflavin, also known as Vitamin B2 or E101, is an orally active and readily absorbed micronutrient. It acts as a precursor to flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which serve as crucial coenzymes for numerous enzymatic reactions and play a vital role in metabolic functions by mediating electron transfer in biological oxidation-reduction reactions.
- Demonstrates a potent cytotoxic effect on HL60 cells after UV irradiation.
- Enhances cell viability and glutathione reductase activity in HepG2 cells.
- Promotes growth in Swiss albino mice.
- Produces antinociceptive, antihyperalgesic, and anti-inflammatory effects in various rat models.
- Inhibits the nociceptive response in mice experiencing acetic acid-induced constriction.
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Medchemexpress LLC Bucladesine (sodium) | 16980-89-5 | 99.4% | 1 ML
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Bucladesine sodium is a stabilized cyclic AMP (cAMP) analog that acts as a selective PKA activator. It increases intracellular cAMP levels and also functions as a phosphodiesterase (PDE) inhibitor. This compound possesses anti-inflammatory activity and has been utilized for impaired wound healing research.
- Acts as a selective PKA activator
- Increases intracellular cAMP levels
- Functions as a phosphodiesterase (PDE) inhibitor
- Exhibits anti-inflammatory activity
- Can be used for impaired wound healing research
- Increases choline acetyltransferase (ChAT) and vesicular acetylcholine transporter (VAChT) mRNA levels in PC12 cells
- Improves spatial memory retention in vivo studies
- Supplied as a white to off-white solid
- Soluble in water and DMSO
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