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Filtered Search Results
Medchemexpress LLC Todralazine hydrochloride | 3778-76-5 | 99.9% | 5 MG
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Todralazine hydrochloride is an anti-hypertensive agent that acts as a β2AR blocker, possessing antioxidant and free radical scavenging activity. It is intended for research use only and not for sale to patients.
- Anti-hypertensive agent
- Acts as a β2AR blocker
- Possesses antioxidant activity
- Possesses free radical scavenging activity
- Intended for research use only
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Medchemexpress LLC Cefmenoxime hydrochloride | 75738-58-8 | 99.3% | 10 MM 1 ML
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Cefmenoxime hydrochloride is a semisynthetic cephalosporin antibiotic. It demonstrates broad-spectrum antibacterial activity against both gram-positive and gram-negative bacteria.
- Targets β-lactam
- Inhibits 90% of tested strains (MIC90) from 0.06 to 8 μg/mL for Enterobacteriaceae
- Effective against *Streptococcus pneumoniae*, *Streptococcus pyogenes*, and *S. aureus*
- Active against *Haemophilus influenzae*, *Neisseria gonorrhoeae*, and *Neisseria meningitidis*
- Improves survival rate in mice infected with lung bacteria
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Medchemexpress LLC Xylometazoline (hydrochloride) | 1218-35-5 | 99.9% | 10 G
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Xylometazoline hydrochloride is an alpha-adrenergic receptor agonist that constricts nasal blood vessels and increases nasal airflow. It is used in nose stuffiness and runny nose research.
- Alpha-adrenergic receptor agonist (Ki=0.05-1.7 μM)
- Constricts nasal blood vessels
- Increases nasal airflow
- Suitable for nose stuffiness research
- Suitable for runny nose research
- Shows affinity for α1A-adrenoceptor and α2B-adrenoceptor in HEK293 cells
- Improves sinusitis in rats in vivo
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Medchemexpress LLC Diphenylpyraline hydrochloride | 132-18-3 | 99.9% | 1 ML
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Diphenylpyraline hydrochloride is a potent histamine H1 receptor antagonist, functioning as an orally active antihistamine agent with antimuscarinic and antiallergic effects.
- Relieves allergic conditions such as rhinitis and hay fever.
- Addresses pruritic skin disorders in vivo.
- Inhibits dopamine uptake in mouse nucleus accumbens slices.
- Elevates extracellular dopamine levels in mouse nucleus accumbens.
- Induces locomotor activation in mice.
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Medchemexpress LLC Phenazopyridine hydrochloride | 136-40-3 | 99.6% | 1 ML
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Phenazopyridine hydrochloride is a competitive SARM1 inhibitor (IC50 145 μM) and a TRPM8 antagonist. It has local anesthetic and analgesic effects, and can promote neuronal differentiation. This product is used to relieve painful symptoms of conditions like cystitis and urethritis, and in the study of traumatic brain injury, peripheral neuropathy, and neurodegenerative diseases.
- Competitive SARM1 inhibitor (IC50 145 μM)
- TRPM8 antagonist
- Exhibits local anesthetic and analgesic effects
- Relieves painful symptoms of cystitis and urethritis
- Promotes neuronal differentiation
- Used in research for traumatic brain injury, peripheral neuropathy, and neurodegenerative diseases
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Medchemexpress LLC Cyclobenzaprine hydrochloride | 6202-23-9 | 99.9% | 5 G
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Cyclobenzaprine (MK130) hydrochloride is an orally active 5-HT2 receptor antagonist that acts centrally to provide skeletal muscle relaxation, alleviate muscle spasms, and reduce pain. It also exhibits antiparasitic activity and is considered promising for research into acute, painful skeletal muscle disorders and infectious diseases.
- Orally active 5-HT2 receptor antagonist
- Acts centrally to provide skeletal muscle relaxation
- Alleviates muscle spasms
- Reduces pain
- Exhibits antiparasitic activity
- Suitable for research into acute, painful skeletal muscle disorders
- Suitable for research into infectious diseases
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Medchemexpress LLC Cyclobenzaprine hydrochloride | 6202-23-9 | MFCD00079039 | 99.95% | 1 ML
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Cyclobenzaprine hydrochloride is an orally active 5-HT2 receptor antagonist. It acts centrally to provide skeletal muscle relaxation, alleviate muscle spasms, and reduce pain. It also possesses antiparasitic activity and holds promise for research in acute, painful skeletal muscle disorders and infectious diseases.
- Orally active 5-HT2 receptor antagonist
- Provides skeletal muscle relaxation
- Alleviates muscle spasms
- Reduces pain
- Possesses antiparasitic activity
- Potential for research in acute, painful skeletal muscle disorders
- Potential for research in infectious diseases
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Medchemexpress LLC Pilocarpine (hydrochloride) | 54-71-7 | 99.92% | 1 G
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Pilocarpine Hydrochloride is a potent M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist, identified for use as a laboratory chemical and in the manufacture of substances.
- Acts as an agonist for M3-type muscarinic acetylcholine receptors
- Relevant for research in cardiovascular disease, neurological disease, and cancer
- Has a purity of 99.92% as determined by LCMS
- Appears as a white to off-white solid
- Recommended storage at 4°C, sealed, and away from moisture
- Unstable in solutions, fresh preparation is recommended
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Medchemexpress LLC Maprotiline (hydrochloride) | 10347-81-6 | 99.99% | 100 MG
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Maprotiline (hydrochloride) (Standard) is the analytical standard of Maprotiline (hydrochloride). It is a highly selective noradrenergic reuptake inhibitor with strong antidepressant, antitumor, and neuropathic pain-relieving effects. It induces cancer cell apoptosis by targeting the ERK signaling pathway and CRABP1. This compound is an analytical standard used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Analytical standard
- Highly selective noradrenergic reuptake inhibitor
- Strong antidepressant effects
- Antitumor effects
- Neuropathic pain-relieving effects
- Induces cancer cell apoptosis by targeting the ERK signaling pathway and CRABP1
- Used in qualitative research experiments
- Used in quantitative research experiments
- Used in methodological research experiments
- Suitable for HPLC, GC, and MS applications
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Medchemexpress LLC Maprotiline hydrochloride (Standard) | 10347-81-6 | 99.9% | 5 MG
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Maprotiline hydrochloride (Standard) is the analytical standard of Maprotiline (hydrochloride). It is a highly selective noradrenergic reuptake inhibitor with strong antidepressant, antitumor, and neuropathic pain-relieving effects. It induces cancer cell apoptosis by targeting the ERK signaling pathway and CRABP1. This compound is an analytical standard used for qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Highly selective noradrenergic reuptake inhibitor
- Strong antidepressant effects
- Antitumor effects
- Neuropathic pain-relieving effects
- Induces cancer cell apoptosis by targeting the ERK signaling pathway and CRABP1
- Used as an analytical standard for qualitative, quantitative, and methodological research experiments
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Medchemexpress LLC Maprotiline (hydrochloride) | 10347-81-6 | 99.9% | 500 MG
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Maprotiline hydrochloride is a highly selective noradrenergic reuptake inhibitor with strong antidepressant, antitumor, and neuropathic pain-relieving effects, exhibiting oral activity. This compound induces cancer cell apoptosis by targeting the ERK signaling pathway and CRABP1.
- Induces cell apoptosis and inhibits cell viability in a dose- and time-dependent manner.
- Inhibits metastasis and restrains migration of liver cancer cells.
- Affects the ERK pathway and inhibits SREBP2 phosphorylation.
- Targets CRABP1 and regulates cholesterol biosynthesis.
- Effectively reduces neuropathic pain in mice.
- Inhibits liver cancer tumor growth in vivo.
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Medchemexpress LLC Maprotiline (hydrochloride) | 10347-81-6 | MFCD00078833 | >99.9% | 50 MG
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Maprotiline hydrochloride is an analytical standard and a highly selective noradrenergic reuptake inhibitor. It exhibits strong antidepressant, antitumor, and neuropathic pain-relieving effects. This compound induces cancer cell apoptosis by targeting the ERK signaling pathway and CRABP1, making it a valuable subject for research in various therapeutic areas.
- Inhibits the growth of Huh7 and HepG2 cells and induces cell apoptosis.
- Inhibits the metastasis of liver cancer cells.
- Targets CRABP1 and regulates cholesterol biosynthesis in HCC cells.
- Restrains HCC cell migration with inhibition of epithelial-mesenchymal transition.
- Inhibits liver cancer tumor growth in mice.
- Effectively reduces neuropathic pain in mice.
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Medchemexpress LLC Propafenone hydrochloride | 34183-22-7 | 98.5% | 5 G
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Propafenone hydrochloride, also known as SA-79 hydrochloride, is an anti-arrhythmic medication used to treat illnesses involving rapid heartbeats such as atrial and ventricular arrhythmias. It functions by slowing the influx of sodium ions into cardiac muscle cells, thereby decreasing their excitability. Propafenone is more selective for cells with a high rate and blocks normal cells more effectively than Class Ia or Ib antiarrhythmics. Unlike typical Class Ic antiarrhythmics, it also exhibits beta-adrenergic blocker activity, which can lead to bradycardia and bronchospasm.
- More selective for cells with a high rate
- Blocks normal cells more effectively than Class Ia or Ib antiarrhythmics
- Exhibits beta-adrenergic blocker activity
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Medchemexpress LLC Propafenone hydrochloride | 34183-22-7 | 98.5% | 1 G
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Propafenone hydrochloride is a class of anti-arrhythmic medication used to treat illnesses associated with rapid heartbeats, such as atrial and ventricular arrhythmias. It works by slowing the influx of sodium ions into cardiac muscle cells, which decreases the excitability of these cells. This compound is more selective for cells with a high rate of activity but also affects normal cells more than Class Ia or Ib antiarrhythmics. It also possesses beta-adrenergic blocking activity, which can lead to bradycardia and bronchospasm.
- Treats atrial and ventricular arrhythmias
- Slows influx of sodium ions into cardiac muscle cells
- Decreases excitability of cardiac cells
- More selective for cells with a high rate of activity
- Possesses beta-adrenergic blocking activity
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Medchemexpress LLC Oxyphencyclimine hydrochloride | 125-52-0 | 99.6% | 50 MG
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Oxyphencyclimine hydrochloride is a new tertiary amine that has been investigated for its effects on the peripheral parasympathetic system. It is provided as a white to off-white solid and is soluble in DMSO at concentrations of ≥ 30 mg/mL. This product is intended for research use only.
- Investigated for effects on the peripheral parasympathetic system
- Molecular weight: 380.91
- Formula: C20H29ClN2O3
- Appearance: White to off-white solid
- Solubility: Soluble in DMSO at concentrations of ≥ 30 mg/mL
- Storage (powder): 4°C, sealed, away from moisture and light
- Storage (in solvent): -80°C for 6 months; -20°C for 1 month
- Related signaling pathways include GPCR/G protein, neuronal signaling, and mAChR
- Classified as a muscarinic acetylcholine receptor (mAChR) antagonist
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