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Filtered Search Results
Medchemexpress LLC Fluorenone | 486-25-9 | 100.0% | 180.20 | 1 KG
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9H-fluoren-9-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is a solid with a light yellow to yellow appearance.
- Formula: C13H8O
- Molecular weight: 180.20
- Purity: 99.97%
- Shipping: Room temperature in continental US
- Storage: Store at room temperature for 3 years; in solvent at -80°C for 2 years or -20°C for 1 year
- Solubility (in vitro): DMSO: 100 mg/mL (554.94 mM)
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Medchemexpress LLC BPO-27 racemate | 1314873-02-3 | 98.5% | 548.34 | 1 ML
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BPO-27 racemate is a potent CFTR inhibitor with an IC50 of 8 nM. This compound is an analogue of PPQ-102.
- Potent CFTR inhibitor with an IC50 of 8 nM.
- R enantiomer inhibits CFTR chloride conductance with an IC50 of 4 nM.
- Both enantiomers show metabolic stability in hepatic microsomes.
- R-BPO-27 binds near the canonical ATP binding site.
- Provides sustained therapeutic concentrations in the kidney in vivo.
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Medchemexpress LLC 2-Bromo-3-methoxycyclopent-2-enone | 14203-25-9 | ≥98.0% | 191.02 | 250 MG
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2-Bromo-3-methoxycyclopent-2-enone is a drug intermediate for the synthesis of various active compounds. This product is for research purposes only and not for human use.
- Molecular weight: 191.02
- Chemical formula: C6H7BrO2
- CAS number: 14203-25-9
- Appearance: Solid
- Color: Off-white to yellow
- Purity: ≥98.0%
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Medchemexpress LLC (1R,2R)-2-PCCA hydrochloride | 1609563-71-4 | 98.1% | 528.56 | C30H39Cl2N3O | 25 MG
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(1R,2R)-2-PCCA hydrochloride is the (1R,2R) diastereomer of 2-PCCA, a research-stage small molecule that functions as a GPR88 receptor agonist. It is used in in vitro pharmacology to characterize GPR88 activity and signaling and is supplied as a hydrochloride salt for laboratory assays.
- Potent GPR88 receptor agonist (EC50 = 3 nM in cell-free assay).
- Shows cellular activity with EC50 = 603 nM in cell-based assays.
- Inhibits GPR88-mediated cAMP production (EC50 = 56 nM) in HEK293 GPR88/GloSensor-22F assays.
- Molecular weight 528.56 and molecular formula C30H39Cl2N3O.
- High enantiomeric purity (98.1% ee) and reported purity 99.0%.
- Available in multiple vial sizes for laboratory research use.
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Medchemexpress LLC Cathepsin inhibitor 1 | 225120-65-0 | 99.3% | 401.89 | C20H24ClN5O2 | 1 ML
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Cathepsin inhibitor 1 is a small-molecule inhibitor of cathepsin proteases for research use. It is offered as a ready-to-use 10 mM solution in DMSO and as solid material, allowing flexible use in biochemical profiling and cellular assays. High purity and a defined molecular weight support reproducible assay performance and accurate dosing.
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Medchemexpress LLC Flibanserin hydrochloride (propan-2-ol) hydrate | 167933-07-5 | MFCD00918402 | 99.0% | 10 MG
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Flibanserin hydrochloride (propan-2-ol) hydrate is the hydrochloride salt hydrate of flibanserin (BIMT-17), an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist used in laboratory research on mood, anxiety, and hypoactive sexual desire disorder (HSDD). It is supplied as a solid, high-purity material intended for preclinical and in vitro studies; not for human use.
- Molecular formula: C20H22ClF3N4O·0.5C3H8O·0.5H2O
- Molecular weight: 465.20 g/mol
- Purity: 99.04%
- Physical state: Solid
- Salt form: Hydrochloride (propan-2-ol) hydrate
- Typical applications: preclinical pharmacology and receptor binding studies
- Available pack sizes: research quantities including 10 MG
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Medchemexpress LLC Benzamidine hydrochloride hydrate | 206752-36-5 | MFCD00066285 | 99.6% | 156.61 g/mol | C7H8N2·HCl·xH2O | 10 G
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Benzamidine hydrochloride hydrate is a reversible competitive inhibitor of trypsin-like serine proteases, supplied as a crystalline hydrated hydrochloride. It is used in biochemical and cell-based assays to inhibit trypsin, tryptase, uPA, Factor Xa, thrombin, and tPA, and has been reported to reduce thymidine incorporation in fibroblasts and to decrease tryptase-stimulated collagen synthesis.
- Reversible competitive inhibitor of trypsin-like serine proteases.
- Reported inhibitory activity against tryptase, trypsin, uPA, Factor Xa, thrombin, and tPA.
- High reported purity (about 99.6%).
- Provided as a hydrate; molecular weight depends on water content.
- Available in small lab pack sizes suitable for research use (e.g., 5 g, 10 g).
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Medchemexpress LLC S-phenylcysteine | 34317-61-8 | MFCD01318758 | 98.8% | 197.25 g/mol | C9H11NO2S | 100 G
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S-Phenylcysteine is a phenyl-substituted derivative of the amino acid cysteine intended for research use. It serves as a synthetic intermediate and building block in biochemical and medicinal chemistry research, suitable for synthesis and analytical workflows.
- Phenyl-substituted cysteine derivative for research use
- High purity: 98.8% as reported by manufacturer
- Molecular formula C9H11NO2S and molecular weight 197.25 g/mol
- Solid appearance, suitable for synthesis and analytical applications
- Available in laboratory-scale pack sizes including 25 g and 100 g
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Medchemexpress LLC Peptone from soya | 91079-46-8 | 100 G
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Peptone from soya is a soybean-derived enzymatic digest used as a nutrient supplement for microbiological and cell culture media. It supplies amino acids, peptides, and other growth factors that support microbial proliferation and influence cellular responses. The product is supplied as a light yellow to light brown powder with recommended storage at room temperature.
- Provides amino acids, peptides, and nitrogen sources for culture media.
- Supports microbial growth and cell-based assays.
- Water-soluble; may require sonication for complete dissolution.
- Offered in multiple pack sizes, including 100 G.
- Store at room temperature; stable under recommended conditions.
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Medchemexpress LLC Vidutolimod sodium | 147063-80-7 | 90.2% | 9612.2 | 1 MG
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Vidutolimod sodium is a CpG-A oligodeoxynucleotide and a Toll-like receptor 9 (TLR9) agonist. It is for research use only.
- Activates plasmacytoid dendritic cells (pDCs)
- Triggers interferon alpha (IFNα) release
- Leads to anti-tumor immune effects
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Medchemexpress LLC Desipramine hydrochloride | 58-28-6 | 99.76% | 50 MG
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Desipramine hydrochloride is a potent inhibitor of norepinephrine transporter (NET), 5-HT transporter (SERT), and dopamine transporter (DAT). It is primarily used in research due to its specific inhibitory activities, with reported Ki values of 4, 61, and 78,720 nM for NET, SERT, and DAT respectively. This high-purity compound (99.76%) is supplied for various in vitro and in vivo applications, and its properties and uses are well-documented in scientific literature.
- Inhibits norepinephrine transporter (NET), 5-HT transporter (SERT), and dopamine transporter (DAT).
- High purity of 99.76%.
- Molecular weight of 302.84.
- Chemical formula is C18H23ClN2.
- Appears as a solid, white to off-white in color.
- Detailed solubility information is available for diverse experimental setups.
- Frequently cited in scientific publications for research applications.
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Medchemexpress LLC 2-Bromo-5-fluoropyridine | 41404-58-4 | 99.9% | 175.99 | 50 G
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2-Bromo-5-fluoropyridine is an intermediate that can undergo Suzuki coupling reaction with Boronic acid and is utilized in the synthesis of GSK1292263A, a GPR119 receptor agonist. This product is intended for research use only.
- Intermediate for chemical synthesis.
- Can be used in Suzuki coupling reactions.
- Used in the synthesis of GSK1292263A, a GPR119 receptor agonist.
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Medchemexpress LLC Ilaprazole (sodium) | 172152-50-0 | 99.5% | 1 ML
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Ilaprazole sodium (IY-81149) is an orally active proton pump inhibitor. It irreversibly inhibits H+/K+-ATPase in a dose-dependent manner with an IC50 of 6 μM in rabbit parietal cell preparation. It is used for the research of gastric ulcers and is also a potent TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor.
- Orally active proton pump inhibitor
- Irreversibly inhibits H+/K+-ATPase
- Potent TOPK inhibitor
- Used for the research of gastric ulcers
- Can be stored long-term under appropriate conditions
- Appearance: solid, white to off-white
- Molecular weight: 388.42
- Formula: C19H17N4NaO2S
- Shipping: room temperature in continental US; may vary elsewhere
- Storage: 4°C, sealed storage, away from moisture and light. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Medchemexpress LLC Tranylcypromine hemisulfate | 13492-01-8 | 99.9% | 1 ML
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Tranylcypromine hemisulfate is an irreversible, nonselective monoamine oxidase (MAO) inhibitor used in the treatment of depression. It also acts as a lysine-specific demethylase 1 (LSD1) inhibitor, capable of suppressing lesion growth and ameliorating generalized hyperalgesia in mouse models of induced endometriosis. This compound exhibits antidepressant effects.
- Irreversible, nonselective monoamine oxidase (MAO) inhibitor.
- Lysine-specific demethylase 1 (LSD1) inhibitor.
- Suppresses lesion growth and ameliorates generalized hyperalgesia.
- Neuroprotective against human Aβ(1-42) oligomer-induced toxicity.
- Protects RGCs from glutamate neurotoxicity-induced apoptosis and oxidative stress.
- Promotes mitogen-activated protein kinase 12 (p38 MAPKγ) expression.
- Enhances RGC survival by attenuating NMDA neurotoxicity.
- Increases cell proliferation in brain regions.
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Medchemexpress LLC Miransertib hydrochloride | 1313883-00-9 | 99.74% | 468.98 | 25 MG
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Miransertib hydrochloride | 1313883-00-9 | 99.74% | 468.98 | 25 MG
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