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Filtered Search Results
Medchemexpress LLC Eprazinone dihydrochloride | 10402-53-6 | 99.0% | 1 ML
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Eprazinone dihydrochloride is an agent with mucolytic, secretolytic, antitussive, and bronchial antispasmodic properties. It acts as a neurokinin 1 receptor (NK1R) ligand. It has potential for the treatment of chronic bronchitis by improving pulmonary function and arterial partial pressure of oxygen.
- Acts as a neurokinin 1 receptor (NK1R) ligand.
- Has mucolytic, secretolytic, antitussive, and bronchial antispasmodic properties.
- Shows potential for chronic bronchitis treatment.
- Improves pulmonary function and arterial partial pressure of oxygen.
- Specifically displaces binding to the NK1R.
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Medchemexpress LLC Cefmetazole sodium | 56796-39-5 | 99.5% | 1 ML
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Cefmetazole sodium is a semisynthetic cephamycin antibiotic that exhibits broad-spectrum antibacterial activity against gram-positive, gram-negative, and anaerobic bacteria. It functions by binding to penicillin binding proteins (PBPs), which interferes with the biosynthesis of bacterial cell walls. This product is intended for research purposes related to gynecologic, intraabdominal, urinary tract, respiratory tract, and skin and soft tissue infections.
- Semisynthetic cephamycin antibiotic.
- Broad-spectrum antibacterial activity.
- Effective against gram-positive, gram-negative, and anaerobic bacteria.
- Interferes with bacterial cell wall biosynthesis by binding to penicillin binding proteins (PBPs).
- Used for research into gynecologic, intraabdominal, urinary tract, respiratory tract, and skin and soft tissue infections.
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Medchemexpress LLC Veratrole (1,2-dimethoxybenzene) | 91-16-7 | 99.5% | 1 KG
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Veratrole (1,2-Dimethoxybenzene) is a key compound widely found in plants that attracts pollinators. Its release exhibits a circadian rhythm, playing a significant role in plant reproduction, species differentiation, and interactions with pollinators. Additionally, Veratrole can be demethylated by cytochrome P-450 in Streptomyces setonii.
- Exists widely in plants.
- Attracts pollinators.
- Plays a role in plant reproduction, species differentiation, and interactions with pollinators.
- Can be demethylated by cytochrome P-450 in Streptomyces setonii.
- No safety issues regarding genotoxicity, repeated-dose toxicity, reproductive toxicity, skin sensitization, phototoxicity/photoallergenicity, and local respiratory toxicity at current use levels.
- Poses no risk to the aquatic environment.
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Medchemexpress LLC 3-Methoxyphenylethylamine | 2039-67-0 | 99.4% | 151.21 | 50 G
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3-Methoxyphenylethylamine is an organic compound utilized as an intermediate for pharmaceuticals, dyestuffs, and liquid crystal materials. It acts as a substrate for cytochrome P450 2D6 (CYP2D6), allowing its use in drug metabolism studies.
- Serves as a model substrate in drug metabolism studies to investigate catalytic mechanisms and substrate selectivity.
- Its oxidation product acts as a norepinephrine precursor.
- Contributes to the nervous system.
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Medchemexpress LLC Cathepsin Z (mouse) recombinant protein, C-terminal His tag | >95.0% | 10 UG
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Recombinant mouse Cathepsin Z (CTSZ) produced in HEK293 cells with a C-terminal His tag. Supplied as a lyophilized powder for biochemical assays and reagent applications; the proenzyme requires activation in acid reducing buffer for functional studies.
- Expression system: HEK293 cells.
- Tag: C-terminal His tag for purification and detection.
- Purity greater than 95% by reducing SDS-PAGE.
- Form: lyophilized powder formulated from PBS, pH 7.4.
- Endotoxin less than 1 EU/μg.
- Molecular weight approximately 38 kDa and glycosylated.
- Activity measured at 715.46 pmol/min/μg after activation.
- Storage: stable at -20°C; aliquot and store at -80°C for long term.
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Medchemexpress LLC Veratraldehyde | 120-14-9 | 166.18 | 1 KG
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Veratraldehyde is an orally active aromatic compound that exhibits antibacterial properties. It can be naturally isolated from the essential oils of plants such as peppermint and ginger. This compound functions as an antibacterial agent by targeting the PilY1 protein and has demonstrated activity against *Pseudomonas aeruginosa*. Additionally, Veratraldehyde is noted for its repellent effects against mosquitoes and ticks and can also be utilized as a flavoring agent.
- Orally active aromatic compound
- Natural origin: isolated from plant essential oils like peppermint and ginger
- Antibacterial agent: effectively targets the PilY1 protein to inhibit bacterial growth
- Activity against *Pseudomonas aeruginosa*
- Repellent effect: acts as a repellent against mosquitoes and ticks
- Flavoring agent
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Medchemexpress LLC Sardomozide dihydrochloride | 138794-73-7 | 99.73% | 303.19 | 100 MG
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Sardomozide dihydrochloride is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM. It is for research use only. Following treatment for 48 h with 3 μM Sardomozide, intracellular SAMDC activity is reduced to 10% of control. When CHO/664 cells are grown in the presence of Sardomozide and treated with DENSPM, vacuole formation is not observed, and these cells are growth-inhibited and contain levels of DENSPM similar to parental CHO cells.
- S-adenosylmethionine decarboxylase (SAMDC) inhibitor
- IC50 of 5 nM
- Reduces intracellular SAMDC activity to 10% of control after 48 h treatment with 3 μM
- Prevents vacuole formation in CHO/664 cells when treated with DENSPM
- Inhibits growth of CHO/664 cells
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Medchemexpress LLC Chloridazon 25g
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Chloridazon is a herbicide with an LD50 value of 76 6 ppm at genotoxicity assay[1]
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Medchemexpress LLC 2-Chloro-3-pyridinol | 6636-78-8 | MFCD00006235 | 99.9% | 129.55 | 1 ML
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2-Chloro-3-pyridinol is a biochemical reagent used as a biological material or organic compound for life science research. It can also be utilized in the synthesis of other active compounds. Additionally, it is identified as a halopyridinol disinfection by-product found in drinking water samples. In vitro studies show that 2-Chloro-3-pyridinol exhibits very low cytotoxicity to human hepatocellular carcinoma HepG2 cells, with an EC50 > 10000 μM.
- Biochemical reagent for life science research.
- Used in the synthesis of other active compounds.
- Identified as a halopyridinol disinfection by-product.
- Exhibits very low cytotoxicity to HepG2 cells.
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Medchemexpress LLC DMT-2′Fluoro-dU Phosphoramidite | 146954-75-8 | 100.0% | C39H46FN4O8P | 25 G
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DMT-2' Fluoro-dU Phosphoramidite is a uridine phosphoramidite with a fluorine in the 2' position. It can be used for nucleoside modification and synthesis of DNA.
- Uridine phosphoramidite
- Contains fluorine in the 2' position
- Used for nucleoside modification
- Used for synthesis of DNA
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Medchemexpress LLC Palbociclib hydrochloride | 571189-11-2 | 99.96% | C24H30ClN7O2 | 1 G
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Palbociclib hydrochloride is an orally active, selective CDK4 and CDK6 inhibitor with IC50 values of 11 nM and 16 nM, respectively. It exhibits potent anti-proliferative activity and induces cell cycle arrest in cancer cells. This compound is suitable for research on HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.
- Selective CDK4 and CDK6 inhibitor
- Potent anti-proliferative activity
- Induces cell cycle arrest in cancer cells
- Used in research of HR-positive and HER2-negative breast cancer
- Used in research of hepatocellular carcinoma
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Medchemexpress LLC E3 ligase Ligand 64 | 2760850-50-6 | ≥98.0% | C₁₂H₁₀BrFN₄O₂ | 25 G
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E3 ligase Ligand 64 is a ligand for E3 ligase, used for the synthesis of RP03707. This product is a solid with a molecular weight of 341.14 and a chemical formula of C₁₂H₁₀BrFN₄O₂. It is intended for laboratory research use only and should be handled by qualified scientists in appropriately equipped facilities. It is classified with several hazards, including acute oral toxicity, skin and eye irritation, and potential respiratory irritation.
- Identified as 2,4(1H,3H)-Pyrimidinedione, 1-(6-bromo-5-fluoro-1-methyl-1H-indazol-3-yl)dihydro-.
- Used for synthesis.
- For research use only.
- Store at room temperature for 3 years; in solvent at -80°C for 2 years or -20°C for 1 year.
- Shipping at room temperature if less than 2 weeks.
- Causes skin and serious eye irritation.
- May cause respiratory irritation.
- Harmful if swallowed.
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Medchemexpress LLC Fluorescein 5-isothiocyanate | 3326-32-7 | 25 G
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Fluorescein 5-isothiocyanate | 3326-32-7 | 25 G
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Ambeed 4Hydroxyphenylboronic acid
4-Hydroxyphenylboronic acid, 71597-85-8, 97%
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Medchemexpress LLC Oxanilide (N,N'-diphenyloxalamide) | 620-81-5 | MFCD00041758 | >98.0% | 240.26 g/mol | C14H12N2O2 | 25 G
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Oxanilide (N,N'-diphenyloxalamide) is an organic intermediate used in the synthesis of quinoline and disulfide derivatives. Supplied as a solid for research applications, it has CAS 620-81-5, formula C14H12N2O2, and a molecular weight of 240.26 g/mol. Available in small laboratory pack sizes and intended for research use only.
- Intermediate for heterocycle and disulfide synthesis.
- Solid form suitable for handling and storage.
- High purity commonly available (>98%).
- Stable under recommended storage conditions.
- Available in multiple small-scale pack sizes for laboratory use.
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