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Filtered Search Results
Apexbio Technology LLC Diphenidol HCl 3254-89-5 10mM (in 1mL DMSO)
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Diphenidol hydrochloride (CAS 3254-89-5) is a small molecule that acts as a nonselective antagonist of muscarinic acetylcholine receptors targeting subtypes M1 through M4 It also inhibits multiple voltage-gated ion channels including sodium (Na ) potassium (K ) and calcium (Ca ) channels thereby modulating neuronal excitability Diphenidol hydrochloride has demonstrated antiarrhythmic activity and is frequently employed in studies investigating the neurophysiological mechanisms underlying vertigo and the pathways involved in antiemetic responses Its polypharmacological profile makes it a suitable tool for research into neural signaling and emesis modulation
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Aobchem AOBCHEM
5000863806 3-BENZYLOXY-4-FLUOROPHENOL 5G
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Apexbio Technology LLC Eletriptan HBr 177834-92-3 10mM (in 1mL DMSO)
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Eletriptan hydrobromide (CAS 177834-92-3) is an orally bioavailable small molecule that acts as a selective agonist for the 5-hydroxytryptamine (serotonin) 5-HT1B and 5-HT1D receptors By activating these receptor subtypes eletriptan hydrobromide modulates cranial blood vessel tone and neuronal signaling implicated in migraine pathophysiology This compound is commonly utilized in preclinical and clinical research to investigate serotonergic modulation of neurovascular function and to explore therapeutic mechanisms relevant to migraine and related neurovascular disorders
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BIOHIPPO
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5000858822 HUMAN BND-35 BIOSIMILAR
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Medchemexpress LLC Smcy HY peptide (738-746) | 207113-06-2 | 1167.34 | 5 MG
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Smcy HY peptide (738-746) is an H2-Dᵇ-restricted peptide corresponding to amino acids 738-746 of the Smcy protein, targeting MHC in the immunology/inflammation pathway. It has a sequence of Lys-Cys-Ser-Arg-Asn-Arg-Gln-Tyr-Leu.
- H2-Dᵇ-restricted peptide
- Corresponds to amino acids 738-746 of Smcy protein
- Targets MHC
- Involved in immunology/inflammation pathway
- Can be stored as powder for up to 2 years at -80°C
- Can be stored in solvent for up to 6 months at -80°C
- Recommended storage conditions are sealed, away from moisture and light, under nitrogen
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000428811 DEAE AGAROSE HP 5ML
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000428963 BASEMENT MEMBRANE MA 5ML
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Medchemexpress LLC ODN 2088 sodium | DNA, d(P-thio)(T-C-C-T-G-G-C-G-G-G-G-A-A-G-T), sodium salt | 1 MG
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ODN 2088 sodium is a potent inhibitor of TLR3, TLR7, and TLR9, showing no cytotoxic effects and inhibiting the release of IFN-α and IL-6. This product is for research use only.
- Purity: 98.82%
- Molecular weight (free acid): 4878
- Appearance: White to off-white solid
- Soluble in H2O at ≥ 25 mg/mL
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Medchemexpress LLC Resminostat hydrochloride | 1187075-34-8 | 99.67% | 385.87 | 5 MG
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Resminostat hydrochloride is a potent inhibitor of HDAC1, HDAC3, and HDAC6, with mean IC50 values of 42.5, 50.1, and 71.8 nM, respectively. It exhibits less potent activity against HDAC8, with an IC50 of 877 nM. This product is for research use only and is not sold to patients.
- Potent inhibitor of HDAC1, HDAC3, and HDAC6
- IC50 values of 42.5, 50.1, and 71.8 nM for HDAC1, HDAC3, and HDAC6 respectively
- Less potent activity against HDAC8
- For research use only
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Medchemexpress LLC Undecane | 1120-21-4 | 25 G
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Undecane is a potent cAMP agonist with anti-allergic and anti-inflammatory activities. It inhibits degranulation and the secretion of histamine and TNF-α. It reverses increased levels of p38 phosphorylation, NF-κB transcriptional activity, and target cytokine/chemokine genes. Undecane can be used for the study of skin inflammatory disorders, such as atopic dermatitis.
- Potent cAMP agonist
- Exhibits anti-allergic and anti-inflammatory activities
- Inhibits degranulation and secretion of histamine and TNF-α
- Reverses p38 phosphorylation and NF-κB transcriptional activity
- Reduces mRNA expression of inflammatory cytokines
- Suitable for studying skin inflammatory disorders
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Medchemexpress LLC Sacubitril sodium | 149690-05-1 | C24H28NNaO5 | 1 ML
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Sacubitril sodium is a potent and orally active neprilysin (NEP) inhibitor, with an IC50 of 5 nM. It enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. It is a component of the heart failure medicine LCZ696 and can be used for the research of heart failure, hypertension, and COVID-19.
- Increases neprilysin-degraded peptides (NPs, ANP, BNP)
- Augments ANP-evoked plasma cGMP levels in normotensive rats
- Produces a dose-dependent antihypertensive effect in Dahl-SS rats
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Medchemexpress LLC LCMV GP (61-80) | 232598-19-5 | 99.6% | 2290.60 | 1 MG
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LCMV GP (61-80) is a peptide fragment derived from lymphocytic choriomeningitis virus (LCMV) glycoprotein (GP), corresponding to amino acids 61-80. This specific epitope is known to induce a CD4+ T-cell response, making it suitable for research applications related to immunology and infection studies.
- Specific epitope induces CD4+ T-cell response
- Solid, white to off-white appearance
- Features a defined sequence: Gly-Leu-Lys-Gly-Pro-Asp-Ile-Tyr-Lys-Gly-Val-Tyr-Gln-Phe-Lys-Ser-Val-Glu-Phe-Asp
- Stimulates splenocytes for detection of LCMV-specific CD4 T cells
- Induces proliferation of antigen-specific CD4 memory T cells
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000428790 PENTAFLUOROPHENOL 100G
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Aobchem AOBCHEM
5000861685 1- 3-BROMO-5-METHYLPHENYL ETHA
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Medchemexpress LLC PHM-27 (human) | 87403-73-4 | 99.1% | 2985.41 | 1 MG
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PHM-27 (human) is a human prepro-vasoactive intestinal polypeptide composed of 27 amino acids. It acts as a potent agonist of the human calcitonin receptor, exhibiting an EC50 of 11 nM. This compound is capable of efficiently enhancing glucose-induced insulin secretion from beta cells through an autocrine mechanism.
- Potent human calcitonin receptor agonist
- Enhances glucose-induced insulin secretion
- 27 amino acid polypeptide
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