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Organic compounds that are directly derived from carboxylic acid, and contain an amide functional group substitution; amide groups contain a carbonyl group bonded to an amino group.
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Iodoacetamide-PEG3-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This click chemistry reagent features an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with Alkyne-containing molecules. It can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.