Carboxylic acid esters
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Medchemexpress LLC PTP1B-IN-3 Diammonium | 2026852-51-7 | C20H28N4O10P2 | 1 ML
PTP1B-IN-3 Diammonium is a potent and selective inhibitor of PTP1B, demonstrating an IC50 of 0.49 nM. It exhibits good selectivity against TCPTP with an IC50 of 330 nM and SHP-2 with an IC50 of 13 μM. This compound has been shown to promote insulin signaling and effectively lower glucose levels in ob/ob mice, making it a valuable tool for research into type 2 diabetes and obesity.
- Potent and selective PTP1B inhibitor
- Shows good selectivity against TCPTP and SHP-2
- Promotes insulin signaling
- Lowers glucose levels in ob/ob mice
- Useful for research of type 2 diabetes
- Useful for research of obesity
