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Organic compounds that contain two carboxyl groups; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from dicarboxylic acids.
MG-101 (ALLN Calpain inhibitor-1 Ac-LLnL-CHO) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins
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Ucf-101 is a selective, competitive inhibitor of the pro-apoptotic serine protease Omi/HtrA2, supplied as a 10 mM solution in DMSO for research use. It inhibits His-Omi with IC50 = 9.5 μM, shows minimal activity against other serine proteases, and is provided with analytical documentation for quality and safety.
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CUDC-101 is a potent multi-targeted inhibitor against HDAC EGFR and HER2 with IC50 of 4 4 nM 2 4 nM and 15 7 nM and inhibits class I/II HDACs but not class III Sir-type HDACs Phase 1
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CUDC-101 is a potent multi-targeted inhibitor against HDAC EGFR and HER2 with IC50 of 4 4 nM 2 4 nM and 15 7 nM and inhibits class I/II HDACs but not class III Sir-type HDACs Phase 1
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Sodium lauroyl glutamate is an anionic amino acid surfactant. It has been noted for its potential to cause irritant contact dermatitis, but also for its possible anti-irritating potential when part of a surfactant mixture on human skin. As a mild surfactant, it is primarily utilized in cleaning products. It has a pH value of 5.41 and demonstrates low irritation to the nude mouse skin.
Anionic amino acid surfactant
Used in cleaning products
Exhibits low irritation to nude mouse skin in vitro
For research use only; not sold to patients
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1 2-Dilauroyl-sn-glycerol (CAS No 60562-15-4) is a synthetic diacylglycerol analog commonly used in biochemical and cellular research to study signal transduction pathways Originating from the glycerolipid family it acts as an activator of protein kinase C (PKC) a key component in various signaling cascades PKC is implicated in cellular processes such as differentiation proliferation and apoptosis This compound exhibits in vitro activity in the nanomolar to low micromolar range facilitating studies on its effects at the molecular level It is often applied in cell models including cultured mammalian cells to investigate cellular responses and in animal studies for its potential therapeutic implications Its consistency in behavior makes it valuable for screening drug candidates targeting PKC pathways Experimental concentrations typically depend on the specific research design allowing for optimization based on the targeted outcomes and biological systems employed
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