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Organic compounds that contain two carboxyl groups; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from dicarboxylic acids.
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Ucf-101 is a selective, competitive inhibitor of the pro-apoptotic serine protease Omi/HtrA2, supplied as a 10 mM solution in DMSO for research use. It inhibits His-Omi with IC50 = 9.5 μM, shows minimal activity against other serine proteases, and is provided with analytical documentation for quality and safety.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
GlyH-101 (CAS 328541-79-3) is a cell-permeable glycinyl hydrazone derivative that acts as a selective inhibitor of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel exhibiting a Ki of 1 4 M By blocking CFTR-mediated chloride transport GlyH-101 serves as a valuable tool for investigating CFTR function in epithelial physiology and pathophysiology as well as for studying mechanisms underlying cystic fibrosis and related disorders involving chloride ion dysregulation
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
MG-101 (ALLN Calpain inhibitor-1 Ac-LLnL-CHO) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More