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Dicarboxylic acids and derivatives

Organic compounds that contain two carboxyl groups; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from dicarboxylic acids.

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TARGETMOL CHEMICALS INC PKUMDL-LC-101-D04 5MG
SDP

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. PKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4) a regulator of iron death. GPX4 activity was increased to 150% of control levels when used at a concentration of 20 uM in a cell-free assay and at a concentration of 61 uM in wild-type but not Gpx4-/- mouse embryonic fibroblast (MEF) extracts.PKUMDL-LC-101-D04 (200 uM) reduced cholesterol peroxide-induced MEF death. purity: 98%

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