Carbimazole (CAS 22232-54-8) is a small-molecule inhibitor targeting thyroid peroxidase (TPO) It is designed to inhibit TPO-mediated iodination and coupling of thyroglobulin tyrosine residues thereby reducing thyroid hormone biosynthesis Carbimazole exerts its biological activity primarily through metabolic conversion to methimazole which suppresses TPO enzymatic function Based on these pharmacological properties Carbimazole holds research potential in studies of hyperthyroidism endocrine modulation experimental neurology and inflammation models