Oxazoles
Medchemexpress LLC An-12-h5 | 1193340-31-6 | 98.0% | 100 MG
An antienterovirus compound that inhibits replication of poliovirus (PV) and enterovirus 71 (EV71). Supplied as a high-purity solid research reagent, it is suitable for in vitro assays and can be formulated for in vivo dosing following the provided protocols.
- Targets replication of poliovirus and enterovirus 71.
- High purity: 98.0%.
- Molecular weight 513.65 g·mol⁻¹; formula C24H23N3O4S3.
- Soluble in DMSO (100 mg/mL) for in vitro applications.
- Available in solid packages including 100 mg and as a 10 mM solution in DMSO.
- Storage guidance provided for powder and solutions to preserve stability.
Medchemexpress LLC Raf1 protein, human (Y340D, Y341D, sf9, His, GST) | ≥80.0% | 10UG
Recombinant human RAF1 protein containing Y340D and Y341D activating mutations. Produced in Sf9 insect cells and expressed with N-terminal His and GST tags, this kinase fragment (residues S306-F648) is supplied as a filtered solution formulated in 50 mM HEPES pH 7.5, 200 mM NaCl, 20% glycerol, and 1 mM DTT. It is designed for biochemical assays and studies of MAPK/ERK signaling.
- Activating Y340D and Y341D mutations enhance kinase activity.
- Expressed in Sf9 insect cells for eukaryotic folding and modifications.
- N-terminal His and GST tags facilitate purification and detection.
- Supplied as a ready-to-use filtered solution; no reconstitution required.
- Formulated for stability with 20% glycerol and a reducing agent.
- Suitable for kinase assays, signaling studies, and protein-protein interaction experiments.
- Store at -80°C and avoid repeated freeze-thaw cycles.
FUJIFILM BIOSCIENCES INC CultureSure 10mmol/L Y-27632
Y-27632 is reagent for cell culture applications including human ES/iPS cell culture It enhances cell viability and reduces cell death during passaging and cryopreservation Y-27632 inhibits contraction of the vascular smooth muscle infiltration of cancer cells and regulation of cell differentiation caused by a signal transduction system of ROCK Enhances survival rate after cryopreservation and cloning efficiency of human ES and iPS cells This product is Y-27632 prepared in water at 10 mmol/l and sterile-filtered No animal-derived matters are used in the process of manufacturing
AURUM PHARMATECH INC AURUM : SN233509 Methyl-oxazol-4-ylmethyl-amine
Methyl-oxazol-4-ylmethyl-amine 50 mg | MFCD11101411 | CAS: 1065073-38-2 | Purity : 95.00%
FUJIFILM BIOSCIENCES INC CultureSure Y-27632
Y-27632 is reagent for cell culture applications including human ES/iPS cell culture Y-27632 is selective and potent ROCK inhibitor Y-27632 plays various roles including contraction of vascular smooth muscle cells via ROCK signaling pathways Furthermore it suppresses the cell death of human embryonic stem cells hESCs and human induced Pluripotent Stem Cells hiPSCs at cell dispersion and that it increases the survival rate of hESCs and hiPSCs during cryopreservation
Selleck Chemical LLC Y-27632
Y-27632 is a selective ROCK1 and ROCK2 inhibitor with a Ki of 140 nM and 300nM in a cell-free assay exhibits 200-fold selectivity over other kinases including PKC cAMP-dependent protein kinase MLCK and PAK
Medchemexpress LLC Dynamin I antibody (YA4184) | 97 kDa | 50 UL
Dynamin I Antibody (YA4184) is a mouse-derived, non-conjugated IgG2a monoclonal antibody targeting Dynamin I. This antibody is suitable for research use only.
- Catalyzes the hydrolysis of GTP and mediates vesicle scission
- Participates in many forms of endocytosis, such as clathrin-mediated endocytosis or synaptic vesicle endocytosis as well as rapid endocytosis (RE)
- Applications include Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), and Enzyme Linked Immunosorbent Assay (ELISA)
- Predicted and observed band size of 97 kDa
Medchemexpress LLC Y-27632 dihydrochloride | 129830-38-2 | MFCD03490488 | 99.9% | 320.26 g/mol | C14H23Cl2N3O | 50 MG
Y-27632 dihydrochloride is an ATP-competitive inhibitor of Rho-associated protein kinases (ROCK I and II) used in cellular and pharmacological research to modulate ROCK signaling. Supplied as a high-purity solid, it is commonly used in cell signaling studies, pharmacodynamic assays, and stem cell culture applications that require ROCK pathway inhibition.
- ATP-competitive inhibitor of ROCK I and II with reported activity in the low hundreds of nanomolar range.
- High purity suitable for research applications.
- Solid form for easy handling and storage.
- Available in research-scale package sizes for laboratory use.
- Applicable to cell signaling, pharmacology, and stem cell culture studies.