Oxazoles

2-(1,3-Oxazol-5-yl)aniline, ≥97%, Thermo Scientific™

CAS: 774238-36-7 Molecular Formula: C9H8N2O Molecular Weight (g/mol): 160.176 MDL Number: MFCD07772822 InChI Key: UZPQWOKKMYUKNI-UHFFFAOYSA-N PubChem CID: 7162068 IUPAC Name: 2-(1,3-oxazol-5-yl)aniline SMILES: C1=CC=C(C(=C1)C2=CN=CO2)N

Medchemexpress LLC (4S)-GLP-1 receptor agonist 14 | 2758659-09-3 | 99.6% | 880.94 | 5 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

(4S)-GLP-1 receptor agonist 14 is a potent and orally active GLP-1 receptor agonist with an EC50 ≤ 20 nM. It is intended for research applications related to diabetes, obesity, metabolic diseases, cardiovascular diseases, liver diseases, and nonalcoholic steatohepatitis (NASH), as well as other conditions associated with the GLP-1 receptor. In vitro, it inhibits OATP1B1 with an IC50 < 1 μM in HEK293 cells. In vivo, a single oral dose at 5 mg/kg in rats demonstrates good pharmacokinetic parameters, with a Cmax of 1700 ng/mL, AUC of 10193 ng·h/mL, and an oral bioavailability (F) of 90%.

• Potent and orally active GLP-1 receptor agonist
• EC50 ≤ 20 nM
• Inhibits OATP1B1 with an IC50 < 1 μM in HEK293 cells
• Exhibits good pharmacokinetic parameters in rats
• Suitable for research on diabetes, obesity, metabolic diseases, cardiovascular diseases, liver diseases, and nonalcoholic steatohepatitis (NASH)