Pyrazoles
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Medchemexpress LLC Dim-c-pphoch3 | 33985-68-1 | 99.4% | 352.43 | 5 G
DIM-C-pPhOCH3 is a Nur77 agonist. Nerve growth factor-induced Bα (NGFI-Bα, Nur77) is an orphan nuclear receptor. This compound has demonstrated significant biological activity:
- Decreases survival and induces apoptosis in RKO colon cancer cells.
- Induces tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein.
- Inhibits cell growth and induces apoptosis markers such as PARP cleavage.
- Inhibits tumor growth in athymic nude mice bearing RKO cell xenografts.
- Soluble in DMSO for in vitro studies.
- Suitable for shipping at room temperature in continental US.
- Provides long-term storage stability as powder and in solvent.
