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Filtered Search Results
Ambeed AMBEED
5000850114 2- METHYLAMINO THIAZOLE 250MG
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Medchemexpress LLC Hth-02-006 | 99.4% | 588.44 | C25H29IN6O3 | 10 MG
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HTH-02-006 is a small-molecule NUAK2 inhibitor (IC50 = 126 nM) used in cellular and animal models to study YAP-driven liver and prostate cancer. It reduces NUAK2-mediated signaling and has demonstrated growth inhibition in YAP-high cancer cells and anti-tumor efficacy in mouse models.
- Target: NUAK2
- IC50 126 nM (NUAK2)
- Purity 99.4%
- Molecular formula C25H29IN6O3
- Molecular weight 588.44
- Form off-white to light yellow solid
- Solubility DMSO 100 mg/mL (in vitro)
- Storage powder -20°C (long term), 4°C (short term); in solvent -80°C (6 months), -20°C (1 month)
- Pack size 10 mg
- Suitable for cellular and in vivo cancer research models
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Medchemexpress LLC 10-ethenyl-19-norprogesterone | 13258-85-0 | 99.7% | 326.47 g/mol | C22H30O2 | 5 MG
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Org OD 02-0 (10-ethenyl-19-norprogesterone) is a steroidal membrane progesterone receptor α (mPRα) selective agonist used in research to probe mPRα-mediated signaling and progesterone-related biology. It activates MAPK signaling and inhibits pituitary prolactin secretion, and is provided as a solid for laboratory use.
- mPRα selective agonist (reported IC50 ≈ 33.9 nM)
- activates MAPK signaling
- inhibits prolactin secretion in the pituitary
- high purity: 99.7%
- molecular formula C22H30O2; molecular weight 326.47 g/mol
- available in small research quantities (example sizes: 1 mg, 5 mg, 10 mg, 50 mg)
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Medchemexpress LLC (1S,2R)-2-amino-3-fluoro-1-(4-((methyl-d3)sulfonyl)phenyl)propan-1-ol | 00-00-0 | 97.3% | 250.30 | C10H11D3FNO3S | 5 MG
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ent-Florfenicol amine-d3 is a deuterium-labeled internal standard of florfenicol amine used as a stable isotope tracer for LC-MS/MS method development and quantitative residue analysis. It is provided in small, high-purity quantities for analytical laboratories measuring veterinary drug metabolites and environmental residues.
- Deuterium-labeled analogue enabling accurate isotopic internal standardization.
- High purity (97.3%) suitable for quantitative analysis.
- Supplied in small, ready-to-use quantities for LC-MS/MS workflows.
- Stable under recommended storage conditions for reproducible results.
- Applicable to veterinary residue and environmental testing.
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eMolecules 84358-13-4 | 1-tert-Butoxycarbonylpiperidine-4-carboxylic acid | Oakwood Chemical | MFCD00076999 | 229.276 | C11H19NO4 | 98.000 | CC(C)(C)OC(=O)N1CCC(CC1)C(O)=O | 1g | 537677767
1-tert-Butoxycarbonylpiperidine-4-carboxylic acid | Oakwood Chemical | 84358-13-4 | MFCD00076999 | 229.276 | C11H19NO4 | 98.000 | CC(C)(C)OC(=O)N1CCC(CC1)C(O)=O | 1g | 537677767
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Medchemexpress LLC PNR-7-02 | 1633660-76-0 | 98.0% | 445.92 | C24H16ClN3O2S | 10 MG
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PNR-7-02 is a small-molecule Pol η (DNA polymerase eta) inhibitor provided for preclinical biochemical and cell-based research. It is supplied as a solid research compound and is not for human or veterinary use.
- Purity 98.0%.
- Molecular weight 445.92 g/mol.
- Chemical formula C24H16ClN3O2S.
- CAS number 1633660-76-0.
- Soluble in dimethyl sulfoxide (DMSO).
- Pack size 10 mg.
- Intended for research use only.
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Selleck Chemical LLC GGTI 298 TFA salt
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GGTI 298 is a geranylgeranyltransferase I inhibitor with ability to arrest human tumor cells in the G1 phase of the cell cycle and induce apoptosis
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eMolecules 111769-26-7 | (3R)-tetrahydrofuran-3-amine | Pharmablock | MFCD08234424 | 87.122 | C4H9NO | 97.000 | N[C@@H]1CCOC1 | 5g | 551186307
(3R)-tetrahydrofuran-3-amine | Pharmablock | 111769-26-7 | MFCD08234424 | 87.122 | C4H9NO | 97.000 | N[C@@H]1CCOC1 | 5g | 551186307
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Medchemexpress LLC tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate | 571188-59-5 | MFCD11594962 | 100.0% | 278.36 | 100 G
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tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate is a drug intermediate used for the synthesis of various active compounds. This product is for research use only and is not intended for sale to patients.
- Drug intermediate for the synthesis of various active compounds.
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eMolecules 306937-37-1 | Methyl 2-(2,5-dimethyl-1,3-thiazol-4-yl)acetate | Combi-Blocks | MFCD02677686 | 185.240 | C8H11NO2S | 98.000 | COC(=O)Cc1nc(C)sc1C | 1g | 117564657
Methyl 2-(2,5-dimethyl-1,3-thiazol-4-yl)acetate | Combi-Blocks | 306937-37-1 | MFCD02677686 | 185.240 | C8H11NO2S | 98.000 | COC(=O)Cc1nc(C)sc1C | 1g | 117564657
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Apexbio Technology LLC PIK-93 593960-11-3 100mg
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PIK-93 (CAS 593960-11-3) is a small-molecule inhibitor targeting PI3K (p110 ) and PI4KIII It is designed to inhibit these kinases thereby modulating phosphoinositide signaling pathways involved in cellular proliferation migration survival intracellular trafficking and membrane dynamics PIK-93 exerts its biological activity through inhibition of PI3K and PI4KIII In cell-based studies PIK-93 demonstrates potent inhibitory activity with IC50 values of 16 nM for PI3K and 19 nM for PI4KIII It also exhibits antiviral activity against poliovirus replication with an EC50 of 0 14 M in PV pseudovirus infection assays Based on these pharmacological properties PIK-93 holds research potential in the study of PI3K/PI4K-mediated cellular signaling oncology and mechanisms of viral replication
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Medchemexpress LLC Maralixibat chloride | 228113-66-4 | 99.61% | 710.41 | 50 MG
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Maralixibat chloride is an orally active ileal bile acid transporter (IBAT) inhibitor. It is used for the research of rare cholestatic liver diseases such as Alagille syndrome (ALGS), progressive familial intrahepatic cholestasis (PFIC), and biliary atresia. Studies have shown Maralixibat chloride to reduce elevated sBA levels, improve liver function, and decrease liver tissue damage in a rat model of cholestasis.
- Orally active ileal bile acid transporter (IBAT) inhibitor
- Used for research of rare cholestatic liver diseases
- Reduces elevated sBA levels
- Improves liver function
- Reduces liver tissue damage in cholestasis models
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Apexbio Technology LLC (±)-Decanoylcarnitine chloride 14919-36-9 50mg
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racemic Baclofen -Decanoylcarnitine chloride is a small-molecule modulator targeting cholinergic systems by engaging acetylcholine receptors including nicotinic and muscarinic subtypes It is designed to influence neurotransmission and lipid metabolism racemic Baclofen -Decanoylcarnitine chloride exerts its biological activity primarily through modulation of acetylcholine receptors and inhibition of -aminobutyric acid (GABA) receptor activity thereby attenuating GABA-mediated inhibitory synaptic currents In neuronal cells and cardiac models such acylcarnitine derivatives demonstrate antiarrhythmic properties post-ischemic insult and modulation of pain signaling involving the phospholipase C-inositol triphosphate pathway Based on these pharmacological properties racemic Baclofen -Decanoylcarnitine chloride holds research potential in cardiac arrhythmia and pain modulation applications
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BIOHIPPO AAV-TH-DIO-hM4D(Gi)-mCherry-WPREs
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Recombinant adeno associated virus expressing hM4D(Gi) fused to mCherry under the TH promoter with WPRE and hGH polyA elements. The Cre and Dre logic configuration enables expression only after recombination, providing precise chemogenetic control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
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eMolecules 1703-07-7 | 6-Chloro-5-methyl-2H-pyridazin-3-one | Combi-Blocks, Inc. | MFCD04971427 | 144.560 | C5H5ClN2O | 97.000 | Cc1cc(=O)[nH]nc1Cl | 1g | 569295024
6-Chloro-5-methyl-2H-pyridazin-3-one | Combi-Blocks, Inc. | 1703-07-7 | MFCD04971427 | 144.560 | C5H5ClN2O | 97.000 | Cc1cc(=O)[nH]nc1Cl | 1g | 569295024
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