Incubator Accessories
Diagnostic Biosystems INHIBIN Inhibin
Inhibin is a dimeric glycoprotein hormone from the TGF-β family made of α and β subunits. This antibody recognizes the 32kDa α subunit of human inhibin. Inhibin α is expressed in a wide variety of human tissues, such as brain, prostate, adrenal, granulose cells of ovary, sertoli cells of testis and in fetoplacental unit.
Diagnostic Biosystems CDX2 CDX2 (EP25)
The caudal-related homeodomain protein 2, CDX-2, is a transcription factor which is expressed in the intestine and is thought to play an important role in the proliferation and differentiation of intestinal epithelial cells. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas, intestinal metaplasia of the stomach and intestinal type gastric cancer. In human colorectal cancer, the expression of both CDX2 and carbonic anhydrase 1, a gene regulated by CDX2, is reduced or absent. CDX-2 is one of the important regulators in defining pathways for coordinate control of drug metabolism in the gastrointestinal tract.
Diagnostic Biosystems HELICOBACTER PYLORI Helicobacter Pylori
This antibody reacts with the 54 kDa (flagellin) of H. pylori. The antibody stains the bacteria present on the surface of the epithelium or in the cytoplasm of the epithelial cells. H. pylori is known to cause peptic ulcer and chronic gastritis in humans.
Diagnostic Biosystems CYTOKERATIN 16 Cytokeratin 16
Cytokeratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I Cytokeratins (Cytokeratins 9 to 23) and one type II Cytokeratins (keratins 1 to 8). The cytokeratin protein plays a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in noninvasive breast carcinomas and normal breast tissue.
Diagnostic Biosystems CADHERIN 17 Cadherin 17
Cadherin 17 is exclusively expressed in the epithelial cells of embryonic and adult small intestine, colon, liver, and pancreatic ducts. It has been reported to be frequently expressed in adenocarcinomas arising in the gastrointestinal tract and pancreas. Owing to its restricted expression in these groups of tumors, cadherin 17 has proven to be a useful immunohistochemical marker for assisting in distinguishing these neoplasms from other malignancies with which they may be confused
Diagnostic Biosystems QUATRO SOL I QuatroSol I 10X Citrate Buffer For Heat Induced Epitope Recovery, pH 6.0 kit/200 Runs
QuatroSol I 10X Citrate Buffer For Heat Induced Epitope Recovery, pH 6.0 kit is designed for use during the heat induced epitope retrieval (HIER) step prior to immunohistochemistry on formalin-fixed paraffin embedded tissue sections. The use of this buffer in combination with heat (often by microwave, water bath, or pressure cooker) has been shown to restore the antigenicity of proteins modified during the formalin fixation of tissue. This buffer is supplied as a 10X stock solution.\n\n
Diagnostic Biosystems SOX10 SOX10 (Melanoma Marker)
SOX10 is widely expressed in normal human tissues including melanocytes and breast tissue. SOX10 is also an important marker in malignant tumors such as melanoma, breast carcinoma, gliomas, and benign tumors such as schwannomas.SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas. In normal tissues, it is expressed in Schwann cells, melanocytes and myoepithelial cells ofsalivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.
Diagnostic Biosystems TRICHOME STAIN Trichome Stain
The Trichrome Stain Kit (Modified Masson’s) is intended for use in the histological visualization of collagenous connective tissue fibers in formalin-fixed tissue sections.
Diagnostic Biosystems PHOSPHOHISTONE H3 PHH3 Phosphohistone H3 (PHH3)
Phosphohistone H3 (PHH3) is a core histone protein, which together with other histones, forms the major protein constituents of the chromatin in eukaryotic cells. In mammalian cells, phosphohistone H3 is negligible during interphase but reaches a maximum for chromatin condensation during mitosis.Immunohistochemical studies showed anti-PHH3 specifically detected the core protein histone H3 only when phosphorylated at serine 10 or serine 28. Studies have also revealed no phosphorylation on the histone H3 during apoptosis.PHH3 can serve as a mitotic marker to separate mitotic figures from apoptotic bodies and karyorrhectic debris, which may be a very useful tool in diagnosis of tumor grades, especially in CNS, skin, gyn., soft tissue, and GIST.
TRIUMPH ENGINEERING GROUP INC CUSTOM TABLE FOR LICONIC INCUB
NC2600960 CUSTOM TABLE FOR LICONIC INCUB
