AWL-II-38.3 is a potent ephrin-A receptor (EphA3) kinase inhibitor. It does not show significant cellular activity against Src-family kinases or b-raf. AWL-II-38.3 fits to LIMK2 and LIMK1 ATP-binding and substrate-binding pockets.
- Potent ephrin-A receptor (EphA3) kinase inhibitor.
- Does not exhibit significant cellular activity against Src-family kinases.
- Does not exhibit significant cellular activity against b-raf.
- Fits to LIMK2 and LIMK1 ATP-binding and substrate-binding pockets.