AWL-II-38.3 is a small-molecule inhibitor of ephrin-A receptor A3 (EphA3) developed for research use. It exhibits potent kinase inhibitory activity against EphA3 with limited cellular activity against Src-family kinases and B-RAF, making it useful for target validation and biochemical assay development.
- Potent EphA3 inhibition in biochemical assays.
- Minimal off-target cellular activity against Src-family kinases and B-RAF.
- High purity suitable for research applications.
- Molecular weight 469.42 g·mol⁻¹ and formula C23H18F3N5O3.
- Soluble in DMSO at high concentration for in vitro use.
- Stable as a powder when stored at cold temperatures; follow solvent storage guidelines.
- Solid, white to light yellow appearance for easy visual confirmation.
- Provided in quantities appropriate for assay development and preclinical studies.