Ladders and Stepstools
Sigma Aldrich Fine Chemicals Biosciences Membrane Scaffold Protein5MG
Nanodisc technology is an approach to render membrane proteins soluble in aqueous SOLUTIONons in anative-like bilayer environment where the membrane proteins remain stable and active. The Nanodisc concept is derived from high density lipoprotein (HDL) particles and their primary protein component apolipoprotein. The Nanodisc is a non-covalent structure of phospholipid bilayer and membrane scaffold protein (MSP) a genetically engineered protein which mimics the function of Apolipoprotein A-1 (ApoA-1).The first MSP MSP1 was engineered with its sequence based on the sequence of A-1 but without the globular N-terminal domain of native A-1. The Membrane Scaffold Protein 1D1 (MSP1D1) variant of MSP1 deletes the first 11 amino acids in the Helix 1 portion (referred to as H0.5 in the accompanying figure) of the original MSP1 sequence. Membrane Scaffold Protein 2N2 (MSP 2N2) is a fusion of MSP1D1 and another MSP variant MSP1D2. MSP1D2 deletes the first 22 amino acids of the original MSP
Electron Microscopy Sciences HINGED PLASTC CONTNRS 9.76ML
These one piece hinged plastic round containers are made from Medical-Grade Polypropylene. Perfect in labs settings for dry or wet samples. They are air and moisture resistant. Have non-allergenis animal-free components and autoclavable (sterilizable) in the presence of aqueous solutions. Food packaging safe. Available in a variety of sizes.
Electron Microscopy Sciences HINGED PLASTC CONTNRS 32.82ML
These one piece hinged plastic round containers are made from Medical-Grade Polypropylene. Perfect in labs settings for dry or wet samples. They are air and moisture resistant. Have non-allergenis animal-free components and autoclavable (sterilizable) in the presence of aqueous solutions. Food packaging safe. Available in a variety of sizes.
Sigma Aldrich Fine Chemicals Biosciences Membrane Scaffold Protein5MG
Nanodiscs are non-covalent structures that contain a phospholipid bilayer and a membrane scaffold protein (MSP) a genetically engineered protein which mimics the function of Apolipoprotein A-1 (ApoA-1). The first MSP MSP1 was engineered with its sequence based on the sequence of A-1 but without the globular N-terminal domain of native A-1. The MSP1E3D1 variant of MSP1 differs from MSP1 in the following facetsIt deletes the first 11 amino acids in the Helix 1 portion (referred to as H0.5 in the accompanying figure) of the original MSP1 sequence3 (which is known separately as MSP1D1).It repeats the Helix 4 (H4) Helix 5 (H5) and Helix 6 (H6) sequences of the original MSP1 sequence between the parent Helix 6 (H6) and Helix 7 (H7) segments of MSP1D1.