ELISA Substrates and Reagents
ABclonal Technology DDR2 Rabbit pAb
This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia.
Rockland Immunochemicals ABTS ELISA PEROXIDASE SUBSTRATE - ABTS-100
ABTS ELISA Peroxidase Substrate (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)) is a chromogenic substrate use to visualize reactivity of certain enzymes, particularly in immunosorbent assays. ABTS ELISA Peroxidase Substrate is commonly used with peroxidases, but is amenable to many other enzymes. In the presence of active enzyme, the substrate becomes a soluble green product detectable at 405nm.
ABclonal Technology 594 anti-h CD235a
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups In addition to the M or N and S or s antigens that commonly occur in all populations about 40 related variant phenotypes have been identified These variants include all the variants of the Miltenberger complex and several isoforms of Sta as well as Dantu Sat He Mg and deletion variants Ena S-s-U- and Mk Most of the variants are the result of gene recombinations between GYPA and GYPB
ABclonal Technology Phospho-MET-Y1234/1235 Rabbit pAb
This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers.
Cayman Chemical 2MethoxyStradIol ELISA Stn 1ea
An analytical reference standard structurally similar to known phytocannabinoids intended for research and forensic applications
Cayman Chemical Phenthyl 4-nPP 5mg
An analytical reference standard that is structurally similar to known opioids; intended for research and forensic applications
Meso Scale Discovery R-PLEX Human HSP27/HspB1 ASYQP
The R-PLEX Human HSP27 (HSPB1) Assay is an ELISA kit for the quantitative measurement of HSP27 in human serum plasma cell culture supernatants cell and tissue lysates and other biological fluids It uses a quantitative sandwich immunoassay technique and comes with a 96-well strip plate that is pre-coated with antibodies specific for HSP27 The detection range for this assay is 15 6-1000 pg/mL with a sensitivity of 5 pg/mL This assay kit provides materials to run up to 40 samples in duplicate and takes around 3 hours to complete Overall the R-PLEX Human HSP27 Assay provides a sensitive high-throughput method for quantifying HSP27 levels in various human sample types
ABclonal Technology Phospho-AKT1-S473 Rabbit pAb
This gene encodes a member of the AKT serine-threonine kinase family (AKT1), which is involved in cell signaling. AKT proteins contain a pleckstrin homology domain, kinase domain, and a regulatory domain. They are phosphorylated by PI3K and play a key role in regulating cell proliferation, survival, metabolism, and angiogenesis. Activated by phosphatidylinositol 3,4,5-trisphosphate (PIP3), AKT proteins regulate numerous cellular functions and are critical for tumor cell survival, inhibiting apoptosis and regulating the mTOR pathway. AKT1 mutations are associated with cancer types, including breast, colorectal, and ovarian cancers, as well as disorders like Proteus syndrome and Cowden syndrome. Multiple spliced variants of this gene exist.
ABclonal Technology Phospho-PPP1R12A-S507 Rabbit pAb
Myosin phosphatase target subunit 1 (MBS) is a key component of myosin phosphatase, which regulates actin-myosin interactions downstream of the Rho GTPase. RhoA, when active in its GTP-bound form, interacts with MBS to control myosin light chain (MLC) phosphorylation, influencing smooth muscle contraction and nonmuscle cell movement. Rho-kinase, activated by GTP-bound RhoA, phosphorylates and inactivates MBS, reducing myosin phosphatase activity. Overexpression of RhoA or activated RhoA increases MLC phosphorylation. Several transcript variants encoding different isoforms of this gene have been identified.