ELISA Substrates and Reagents
Cayman Chemical THUNDRTotal RPS6 TRFRET C 4800
Sandwich TR-FRET immunoassay for semi-quantitative detection of Total Ribosomal Protein S6 (both phosphorylated and non-phosphorylated RPS6) in cell lysates.
ABclonal Technology Phospho-NF-B2-S866/S870
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB) The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner The p100 full-length protein is co-translationally processed into a p52 active form Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas some of which may result in the formation of fusion proteins There is a pseudogene for this gene on chromosome 18 Alternative splicing results in multiple transcript variants
ABclonal Technology Phospho-Akt-S473 Rabbit mAb
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts AKT1 and the related AKT2 are activated by platelet-derived growth factor The activation is rapid and specific and it is abrogated by mutations in the pleckstrin homology domain of AKT1 It was shown that the activation occurs through phosphatidylinositol 3-kinase In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine threonine kinase AKT1 which then phosphorylates and inactivates components of the apoptotic machinery Mutations in this gene have been associated with the Proteus syndrome Multiple alternatively spliced transcript variants have been found for this gene [provided by RefSeq Jul 2011]
Meso Scale Discovery R-PLEX Human GDF-15 ASYQP
The Meso Scale Discovery R-PLEX Human GDF-15 Assay is a multiplex immunoassay panel that allows simultaneous quantitative measurement of GDF-15 in human serum plasma and cell culture supernatants It utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision This assay requires 50 L or less sample volume and can be fully automated on the MSD instrument platforms The GDF-15 assay measures a range of 50-100 000 pg/mL with minimal cross-reactivity to related analytes It is intended for research use only to aid in understanding GDF-15 biology and disease processes
Meso Scale Discovery R-PLEX Human Jagged-1 ASYQP
The R-Plex Human Jagged-1 Assay Kit from Meso Scale Discovery is a multiplex immunoassay that measures Jagged-1 levels in human serum plasma and cell culture supernatants The assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision This kit includes a 96-well plate coated with capture antibody detection antibody read buffer wash buffer blocker solutions calibrator and controls The assay has a sensitivity of 0 3 ng/mL and requires 25 L sample size The kit has been validated on the MESO QuickPlex SQ 120 instrument
Seracare Life Sciences Inc WASH SOLUTION CONCENTRATE
Convenient 20X concentrate containing imidazole-buffered saline and Tween 20. Product contains 1 x 1L bottle, enough to prepare 20 liters of working solution. Suitable for ELISA, blotting and immunohistochemistry applications.
ABclonal Technology Phospho-MST1-T183-MST2-T180
This gene encodes a serine threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor Cleavage of the protein product by caspase removes the inhibitory C-terminal portion The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis Multiple transcript variants encoding different isoforms have been found for this gene
Cell Signaling Technology Mitochondrial Membrane Potential Assay Kit (II) 1 Kit
Mitochondrial Membrane Potential Assay Kit (II) 1 Kit
Sigma Aldrich Fine Chemicals Biosciences 3,3',5,5'-Tetramethylbenzidine >=98% (TLC) | 54827-17-7 | MFCD00007748 | 1G
3,3',5,5'-Tetramethylbenzidine >=98% (TLC) | Purity: >=98% (TLC) | Mol Wt: 240.34 | 54827-17-7 | MFCD00007748 | 1G
ABclonal Technology Phospho-ErbB3/HER3-Y1289
This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases It has a neuregulin binding domain but lacks an active kinase domain so it cannot directly signal into the cell However it forms heterodimers with other EGFR family members that possess kinase activity activating pathways that regulate cell proliferation and differentiation Gene amplification or overexpression is observed in various cancers including prostate bladder and breast tumors Alternate splice variants of this gene encode different isoforms one of which lacks the intermembrane region and is secreted to modulate the activity of the membrane-bound form Additional splice variants have been identified but not fully characterized