Clarion™ 10-S50M - Hydrated Gel Filtration Columns for Purification, Desalting, and Buffer Exchange. Designed to rapidly and efficiently remove small molecules (salts, dyes, ammonia, haptens, biotin) from large molecules (antibodies, enzymes, and other proteins). High performance, lower cost replacement of Cytiva MidiTrap™ columns. The ultrapure gel and specially treated sinter frits ensure outstanding resolution, minimized cross-contamination, and high selectivity. The gel matrix is SorbaDex™-25, a beaded composite material comprised of ultrapure, cross-linked dextran optimized for gravity flow.