The Grid Prep Block is a medical-grade aluminum support block designed to physically support up to five cryo-electron microscopy grids during a variety of surface treatment protocols, with a primary focus on plasma activation. Its ergonomic design includes side finger grooves for a secure grip, numbered support locations for easy tracking, and troughs that provide simple tweezer access both above and below the grid. This product offers a simple, reliable, and efficient means of handling, transporting, and surface-treating grids prior to cryocooling. By providing dedicated support for your grids, the Grid Prep Block helps to streamline your sample preparation workflow and improve the consistency of your results.