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YTK-105 is a small-molecule ligand that binds the p62-ZZ domain and activates p62-dependent selective macroautophagy. Intended for research use, it is characterized by a reported purity of 98.81%, molecular formula C16H19NO2, and molecular weight 257.33 g/mol. The compound is used in autophagy-targeting studies and as a scaffold for degrader design.
Binds the p62-ZZ domain and modulates selective macroautophagy.
High reported purity suitable for biochemical and cell-based assays.
Characterized molecular formula and weight support reproducible experiments.
Suitable as a scaffold for autophagy-targeting probe and degrader design.
Available in milligram-scale quantities for laboratory workflows.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
This item has a minimum qty of 3 per supplier requirements. Mapleson E Breathing Circuit, Tube-outside-a-tube circuit. The fresh gas tube is outside the larger diameter downtube.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
An important anesthesia parameter is monitoring the proper airway pressure in the patient. A Manometer is a standard piece of equipment on all anesthesia machine used to measure this pressure in CMs of H2O. However, the Manometer on an anesthesia machine is not utilized on non-breathing circuits as it is bypassed. Non rebreathing circuits are used on smaller more fragile patients. There is a higher risk of inadvertent alveoli damage or barotrauma when "bagging" or manually ventilating a patient. There have been cases of pneumothorax. The flush valve on an anesthesia machine will immediately push up oxygen flow to 15L at 50psi into a small non breathing circuit. The new in line manometer gives accurate airway pressure to avoid harmful over inflation, but still ensure adequate ventilation is achieved. • Works on common non-rebreathing circuits • Simple to use - detach rebreathing bag and insert Manometer (directions included)
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
YTK-105 is a small-molecule ligand of the p62 (SQSTM1) ZZ domain that activates p62-dependent selective macroautophagy. It is intended as a research reagent for autophagy pathway studies and for use in AUTOTAC design.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
YTK-105 is a small-molecule ligand of the p62 (SQSTM1) ZZ domain that activates p62-dependent selective macroautophagy. It is provided as a research tool for studying autophagy pathways and for designing AUTOTAC degraders.
Activates p62-dependent selective macroautophagy.
Useful as a probe for AUTOTAC design.
Molecular formula C16H19NO2; molecular weight 257.33 g·mol-1.
High purity (98.81%) in viscous liquid form.
Highly soluble in DMSO (≈175 mg/mL); ultrasonic agitation recommended.
Storage: pure form -20°C for long-term; in solvent -80°C short-term.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More