Complex Aldehydes

Sigma Aldrich Fine Chemicals Biosciences 5 Bromo 2 deoxy uridine La

The kit is used for the detection of BrdU incorporated into cellular DNA using immunofluorescence microscopy. It is used for the detection of DNA synthesis by either in vitro labeling of cells or organ cultures or by in vivo labeling in which frozen or paraffin-embedded tissue sections must be prepared prior to fixation.Normally binding of the antibody is only achieved by denaturation of the DNA. This is usually obtained by exposing the cells to acid base or heat. These procedures result in destruction of cell integrity including cell morphology and surface and cytoplasmatic markers.The BrdU Labeling and Detection Kit I avoids these problems. The antibody preparation contains specific nucleases which allows access to BrdU after fixation in acidic ethanol. Therefore also simultaneous detection of other markers (double staining) is possible.

Apexbio Technology LLC 4-Thio-dTTP 50ul (100 mM)

4-Thio-dTTP is a nucleotide analog structurally similar to thymidine triphosphate (dTTP) It incorporates into DNA strands during enzymatic synthesis modifying nucleic acid interactions and affecting the activities of enzymes involved in DNA replication and repair 4-Thio-dTTP exerts its biological activity through incorporation into DNA enabling the study of DNA polymerase fidelity replication kinetics enzyme-substrate interactions and mechanisms of DNA damage responses Based on these biochemical properties 4-Thio-dTTP holds research potential in applications such as investigating DNA synthesis regulation enzymatic mechanisms and pathways related to cancer and genomic instability

Apexbio Technology LLC 4-Thio-dTTP 100ul (100 mM)

4-Thio-dTTP is a nucleotide analog structurally similar to thymidine triphosphate (dTTP) It incorporates into DNA strands during enzymatic synthesis modifying nucleic acid interactions and affecting the activities of enzymes involved in DNA replication and repair 4-Thio-dTTP exerts its biological activity through incorporation into DNA enabling the study of DNA polymerase fidelity replication kinetics enzyme-substrate interactions and mechanisms of DNA damage responses Based on these biochemical properties 4-Thio-dTTP holds research potential in applications such as investigating DNA synthesis regulation enzymatic mechanisms and pathways related to cancer and genomic instability

Medchemexpress LLC 2′-deoxy-4-thiouridine | 5580-20-1 | 99.8% | 244.27 g·mol⁻¹ | C9H12N2O4S | 10 MG

4-Thio-2'-deoxyuridine is a thio-substituted deoxyuridine nucleoside analog used as a probe in nucleic acid chemistry, photochemistry, and cellular studies. The sulfur substitution at C4 gives distinct photophysical and base-pairing properties that facilitate mechanistic, structural, and labeling experiments.

• High purity (99.8%) suitable for research applications.
• Available as a solid powder and as a 10 mM solution in DMSO.
• Offered in multiple package sizes to support small-scale and bulk work.
• Stable under defined storage conditions for long-term and in-solvent storage.
• Well characterized with CAS number and molecular formula for unambiguous identification.

Medchemexpress LLC 4-thio-2'-deoxyuridine | 5580-20-1 | MFCD00058457 | 99.8% | 244.27 g·mol⁻¹ | C9H12N2O4S | 25 MG

4-Thio-2'-deoxyuridine is a purine nucleoside analog used in biochemical and cellular research to probe nucleic acid chemistry and antitumor mechanisms. It can inhibit DNA synthesis and promote apoptosis in experimental systems. Supplied as a light yellow solid with high reported purity, the compound is available in small milligram packages and as ready-to-use DMSO solutions for assay development and screening.

• Purine nucleoside analog for research applications.
• Molecular formula C9H12N2O4S; MW 244.27 g·mol⁻¹.
• CAS number 5580-20-1 for unambiguous identification.
• High purity (reported 99.78%).
• Solid form; light yellow to yellow appearance.
• Storage recommendations provided for powder and solvent solutions.
• Available in small packaging sizes, including 25 mg.
• Concentration options supplied for solution-based assays (e.g., DMSO stocks).