Glyoxylic acid, 50% w/w aq. soln.

Description

CAS: 298-12-4 | C2H2O3 | 74.035 g/mol

Glyoxylic acid is used in Hopkins Cole reaction, which is used in the detection of tryptophan in proteins. It reacts with phenol to get 4-hydroxymandelic acid, which on further reaction with ammonia gives hydroxyphenylglycine, as a precursor to the drug amoxicillin. It is also used as a starting material for the preparation of 4-hydroxyphenylacetic acid, which is used to get atenolol. It is involved in the production of agrochemicals, aromas, cosmetic ingredient and pharmaceutical intermediate. It is also used in water purification and in the preservation of food. Further, it is employed as precursor in the synthesis of iron chelates. In addition to this, it serves as an intermediate of varnish material and dyes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Glyoxylic acid is used in Hopkins Cole reaction, which is used in the detection of tryptophan in proteins. It reacts with phenol to get 4-hydroxymandelic acid, which on further reaction with ammonia gives hydroxyphenylglycine, as a precursor to the drug amoxicillin. It is also used as a starting material for the preparation of 4-hydroxyphenylacetic acid, which is used to get atenolol. It is involved in the production of agrochemicals, aromas, cosmetic ingredient and pharmaceutical intermediate. It is also used in water purification and in the preservation of food. Further, it is employed as precursor in the synthesis of iron chelates. In addition to this, it serves as an intermediate of varnish material and dyes.

Solubility
Miscible with ethanol. Slightly miscible with ether and benzene. Immiscible with esters.

Notes
Incompatible with metals, alkalies, strong oxidizing agents and strong bases.

Specifications

Chemical Identifiers

• CAS: 298-12-4
• Molecular Formula: C2H2O3
• Molecular Weight (g/mol): 74.035
• MDL Number: MFCD00006958
• InChI Key: HHLFWLYXYJOTON-UHFFFAOYSA-N
• Synonym: glyoxylic acid, 2-oxoacetic acid, oxoacetic acid, oxoethanoic acid, glyoxalic acid, formylformic acid, acetic acid, oxo, oxalaldehydic acid, glyoxylate, alpha-ketoacetic acid
• PubChem CID: 760
• ChEBI: CHEBI:16891
• IUPAC Name: oxaldehydic acid
• SMILES: C(=O)C(=O)O

• Melting Point: -93°C
• Density: 1.339
• Boiling Point: 111°C
• Quantity: 250 g
• UN Number: UN3265
• Solubility Information: Miscible with ethanol. Slightly miscible with ether and benzene. Immiscible with esters.
• Formula Weight: 74.04
• Concentration or Composition (by Analyte or Components): 50% w/w aq. soln.
• Chemical Name or Material: Glyoxylic acid

Safety and Handling

Hazard Category	H290-H314-H317-H318
Hazard Statement	GHS H Statement H314-H317 Causes severe skin burns and eye damage. May cause an allergic skin reaction.
Precautionary Statement	P234-P260-P264b-P272-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P333+P313-P363-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: III; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
EINECSNumber	206-058-5
TSCA	Yes
Recommended Storage	Keep cold

SDS

RUO – Research Use Only