Oligonucleotides
Cayman Chemical 17R 18S-EpETE 500ug
An EPA metabolite and activator of KCa1.1/BK channels; increases the potassium current amplitude by 15-fold in isolated rat cerebral artery VSMCs at 50 nM; has negative chronotropic effects in NRCMs (EC50 = ~1-2 nM) and prevents calcium-induced increases in NRCM spontaneous beating
Biotium CD43 (T-Cell Marker) (rSPN/1094), CF740 conjugate, 0.1mg/mL
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low ab
Cayman Chemical Cre mRNACap-1m1 1mg
An mRNA for the expression of Cre; encapsulation in LNPs can be used for mRNA delivery and expression of Cre in vitro or in vivo
Medchemexpress LLC ODN 1826 | 202668-42-6 | 97.24% | 6364.10 | 1 MG
ODN 1826 is a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist. It induces NO and iNOS production, enhances apoptosis, and immune surveillance. It also increases aortic atherosclerotic plaque size and exhibits antitumor activity against lung cancer, glioma, and melanoma.
- Induces nitric oxide and iNOS production in macrophages
- Enhances apoptosis and immune surveillance
- Increases aortic atherosclerotic plaque size in a chronic vascular injury mouse model
- Exhibits antitumor activity against lung cancer, glioma, and melanoma
- Delays growth of subcutaneously implanted gliomas and increases infiltration of macrophages and B cells into tumors
Alkali Scientific DNA & RNA Elution Buffer (EB Buffer) for PCR, Plasmid & Spin Column Cleanup, 500mL
DNA & RNA Elution Buffer is a high-purity solution designed for efficient recovery of nucleic acids during purification workflows. It is commonly used in spin column-based extraction kits for eluting DNA and RNA from silica membranes after washing steps. The buffer is formulated to be PCR compatible, ensuring that eluted nucleic acids can be directly used in downstream applications such as PCR amplification, qPCR, sequencing, and cloning without additional cleanup. Its low ionic strength helps maximize recovery while maintaining nucleic acid stability. This buffer is widely used in molecular biology laboratories for plasmid purification, genomic DNA extraction, and RNA isolation procedures where reliable and contaminant-free elution is required.
Cayman Chemical Cre mRNACap-1m1 100ug
An mRNA for the expression of Cre; encapsulation in LNPs can be used for mRNA delivery and expression of Cre in vitro or in vivo
Biotium EZH2 / KMT6(EZH2/2536), Biotin conjugate, 0.1mg/mL
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium EZH2 / KMT6(EZH2/2536), Biotin conjugate, 0.1mg/mL
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Cayman Chemical ANTIBODY SET2 50mg
A TRPV2 inhibitor (IC50 = 0.46 µM); selectively inhibits 2-APB-induced currents in a patch-clamp assay using HEK293T cells overexpressing TRPV2 at 0.3 or 1 µM over HEK293T cells overexpressing TRPV1 or TRPV3 at 3 or 10 µM; reduces LPA-induced migration in PC-3M prostate cancer cells at 20 µM; reduces LPA-induced increases in current in a patch-clamp assay using HEK293T cells