Oligonucleotides
Biotium SOX9 / SRY-box 9(rSOX9/2288), CF488A conjugate, 0.1mg/mL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19, 000, full-length human proteins. Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Nucleus (Potential). Campomelic dysplasia (CMD1) : Rare, often lethal, dominantly inherited, congenital osteo-chondrodysplasia, associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones, unusually small scapulae, deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate, micrognathia, flat face and hypertelorism are common. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and phot
Abcam Spermine tetrahydrochloride, polyamine used for precipitation of DNA, 1G
MW 348.19 g/mol. Spermine is a biogenic polyamine formed from spermidine and occurs in almost all tissues. It is essential for both neoplastic and normal tissue growth. Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure. Spermine tetrahydrochloride is used for precipitation of DNA from low salt aqueous buffers.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical DNA TopoIsomRase IIaCTRm 100uL
A ganglioside enriched in lipid rafts associates with growth factor receptors and is required for TrkA expression on the cell surface interacts with other proteins to increase calcium influx affecting various calcium-dependent processes including inducing neuronal outgrowth during differentiation acts as a receptor for cholera toxin and the heat-labile enterotoxin from E. coli accumulates in neurons in ganglioside GM1 gangliosidosis levels are decreased in the substantia nigra pars compacta in postmortem brain from patients with Parkinsons disease
Waters Corp Reverse Sample Cone, 0.25 mm Aperture, Mass Spectrometry
This replacement reverse sample cone features a 0.25 mm aperture. It is designed for use in Mass Spectrometry systems, particularly the Xevo TQ-S cronos.
- Replacement part
- 0.25 mm aperture
- Designed for MS systems
- Mechanical component
- Replace as required
BIOHIPPO AAV-ChAT-hChR2(H134R)-EGFP-WPRE-hGH-polyA
Recombinant adeno associated virus expressing hChR2(H134R) fused to EGFP under the ChAT promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Cayman Chemical Oct4 TrnscrIptIon Factr96
Oct4 is an essential regulator of embryonic stem cell pluripotency and used as a marker for undifferentiated cells. It also plays a role in gene expression, DNA repair and/or replication, signal transduction and tumorigenesis. Cayman’s Oct4 Transcription Factor Assay is a non-radioactive, sensitive method for detecting specific transcription factor-DNA binding activity in nuclear extracts. A 96-well enzyme-linked immunosorbent assay (ELISA) replaces the cumbersome radioactive electrophoretic mobility shift assay (EMSA). A specific double-stranded DNA (dsDNA) sequence containing the Oct4 response element is immobilized onto the wells of a 96-well plate. Oct4, contained in a nuclear extract, binds specifically to the Oct4 response element. Oct4 is detected by the addition of a specific primary antibody directed against Oct4. A secondary antibody conjugated to HRP is added to provide a sensitive colorimetric readout at 450 nm.
LICOR IRDye 700 CREB Consensus Oligonucleotide (25 uL)
IRDye 700 oligonucleotides are supplied as 25 µL of 50 nM (or 50 fmol/µL) double-stranded DNA. CREB proteins are cellular transcription factors activated by phosphorylation of various kinases that bind to certain DNA sequences. For this reason, it is a common oligonucleotide used in EMSA to assess protein binding.
Cambridge Isotope Laboratories CAMBRIDGE ISOTOPE LABORATORIES
NC3909843 ISOTOPICALLY LABELED STANDARD
Cayman Chemical TrnscrIPTN FCTR Oct4 Pos 150uL
An ERa degrader (IC50 4.1 nM) inhibits estradiol-induced ERa transcriptional activity in a reporter assay using T47D cells at 1 or 10 nM decreases the proliferation of MCF-7 and T47D cells and tamoxifen-resistant MCF-7 and T47D cells (IC50s 0.0032 0.0062 0.069 and 0.037 nM respectively)