Oligonucleotides
Cayman Chemical TFF1 trefoil factor 1 or pS2
An alkaloid inhibits the growth of human A375 A431 A549 MES-SA and MCF-7 cells (IC50 3 nM for all) inhibits hypoxia-induced gene expression in an HRE reporter assay (IC50 8.7 nM) prevents lesion formation in TMV-infected tobacco plants at 500 Ug/ml inhibits protein synthesis by yeast and mammalian ribosomes
Cayman Chemical Flos Sopoa matuus Toxutn 10g
A flavonoid with diverse biological activities; reduces D-galactose-induced increases in renal MDA levels and decreases in renal Cu/Zn SOD, catalase, and GPX activities in mice at 150 mg/kg per day, as well as attenuates D-galactose-induced increases in renal levels of NF-κB p65, iNOS, COX-2, and EP2 levels; reduces blood glucose levels, plasma triglyceride levels, heart rate, and blood pressure in a rat model of STZ-induced type 2 diabetes at 150 mg/kg per day; prevents the loss of dopaminergic neurons in the SNC and reduces apomorphine-induced contralateral rotations in a rat model of Parkinson’s disease induced by 6-OHDA at 150 mg/kg per day
Biotium pS2(GE2), CF740 conjugate, 0.1mg/mL
This antibody recognizes a polypeptide of 6.5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is localized between aa57-84 of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an incr
Biotium CD43(SPN/839), CF740 conjugate, 0.1mg/mL
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low ab
Cayman Chemical GrIes Reagent R1 1ea
Griess Reagent component for determination of nitrite in aqueous solutions.
Biotium DNA Ligase 1(1A9), 0.2mg/mL
DNA Ligase I maintains the major DNA Ligase activity in proliferating cells by joining Okazaki fragments during lagging strand DNA replication. Human DNA Ligase I also has an essential role in DNA repair pathways, where it catalyzes the formation of phosphodiester bonds between adjacent 5' phosphoryl and 3' hydroxy termini at single breaks in duplex DNA molecules. In addition, DNA Ligase I plays a role in sealing nicks during excision repair. Similar to other DNA ligases, DNA Ligase I is built around a common catalytic core. Increased levels of DNA Ligase I are found in human tumors, as compared to benign tissues, as well as in peripheral blood lymphocytes. DNA Ligase I activity is altered in the chromosomal breakage deficit Bloom's syndrome (BS). Individuals with BS either have decreased levels of abnormally thermolabile DNA Ligase I or possess a dimeric form of this enzyme. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. C
INTACT GENOMICS INC igScript™ Glycerol-free Reverse Transcriptase 10,000 units (200 u/µl)
igScript™ Glycerol-free Reverse Transcriptase is a recombinant Moloney Murine Leukemia Virus (MMLV) reverse transcriptase with reduced RNase H activity. It is highly efficient at producing full-length cDNA from long RNA templates. igScript RT is an RNA-directed DNA polymerase which lacks 3´ → 5´ exonuclease activity and is capable of producing cDNA from as little as 50 pg of total RNA for real-time RT-PCR analysis and other applications.Benefits: Recombinant MMLV reverse transcriptase with greatly reduced RNase H activity. Active at temperatures up to 55°C. Highly efficient at producing full-length cDNA from as little as 50 pg of total RNA.Product Includes: igScript™ Glycerol-free Reverse Transcriptase 10x igScript™ RT Reaction BufferStorage Temperature: –80 °C
Medchemexpress LLC SLC1A5/ASCT2 Antibody (YA1180) | 10 UL
SLC1A5/ASCT2 Antibody (YA1180) is a rabbit-derived, non-conjugated IgG monoclonal antibody that specifically targets SLC1A5/ASCT2. This antibody is intended for research use only and aids in the study of sodium-coupled antiporters of neutral amino acids, which are crucial for cellular transport processes.
- Rabbit host
- Recombinant, monoclonal clonality
- Human species reactivity
- Affinity purified
- Non-conjugated
- IgG isotype
- Liquid appearance
- IHC-P (Immunohistochemistry-Paraffin) application
- Stored at -20°C for 1 year
- Formulated in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide, and 0.05% BSA.
Biotium SOX9 / SRY-box 9(rSOX9/2288), CF405S conjugate, 0.1mg/mL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19, 000, full-length human proteins. Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Nucleus (Potential). Campomelic dysplasia (CMD1) : Rare, often lethal, dominantly inherited, congenital osteo-chondrodysplasia, associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones, unusually small scapulae, deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate, micrognathia, flat face and hypertelorism are common. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and phot
Biotium SOX9 / SRY-box 9(SOX9/2287R), CF405S conjugate, 0.1mg/mL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19, 000, full-length human proteins. Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Nucleus (Potential). Campomelic dysplasia (CMD1) : Rare, often lethal, dominantly inherited, congenital osteo-chondrodysplasia, associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones, unusually small scapulae, deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate, micrognathia, flat face and hypertelorism are common. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and phot
American Research Products Inc PrEST Antigen AQP2
PrEST Antigen AQP2 antigen APrEST83680 for aquaporin 2 (collecting duct) Recombinant protein fragment of Human AQP2