Oligonucleotides
Cayman Chemical HIston H3CItrulInated R2 100ug
A symmetric bis-glycolamide that inhibits the eIF2a phosphorylation-mediated unfolded protein response (IC50 5 nM in a cell-reporter assay) passes through the blood-brain barrier and significantly enhances learning and memory in mice and rats
Cayman Chemical 1113 14dIhydro15keto Pro 500ug
A carboxylic acid metabolite of AB-CHMINACA intended for forensic and research applications
Cayman Chemical GW 4869 hydrochloride hydrat
A racemic mixture of hydroperoxides derived non-enzymatically from linoleic acid through the action of reactive oxygen species has limited direct biological actions such as the activation of lipoxygenases normally is rapidly reduced to ( )13-HODE can also be metabolized to unsaturated aldehydes that can in turn covalently bind to DNA amino acids and proteins
Cayman Chemical VHL LIgnd 1hydrochlorIde 10mg
An active metabolite of caffeine an adenosine A1 and A2 receptor antagonist (Kis 35 and 22 UM respectively) increases striatal cGMP and extracellular striatal dopamine levels and locomotor activity as well as inhibits motor depression induced by CPA or CGS 21680 in rats not habituated to caffeine at 30 mg/kg promotes wakefulness and increases locomotor activity and core temperature in narcoleptic transgenic mice without increasing behavioral anxiety
Cayman Chemical VHL LIgnd 1hydrochlorIde 50mg
An active metabolite of caffeine an adenosine A1 and A2 receptor antagonist (Kis 35 and 22 UM respectively) increases striatal cGMP and extracellular striatal dopamine levels and locomotor activity as well as inhibits motor depression induced by CPA or CGS 21680 in rats not habituated to caffeine at 30 mg/kg promotes wakefulness and increases locomotor activity and core temperature in narcoleptic transgenic mice without increasing behavioral anxiety
Cayman Chemical N4TosylLargInIn methyl e 5g
A selective inverse agonist of ERRa (IC50 ~300-500 nM) blocks ERRa/PGC-1a-dependent signaling suppressing the expression of MAO A and B induces proteasomal degradation of ERRa and potentiates the degradation of ERa by fulvestrant
Cayman Chemical 11-deoxy ProstaglndIn F2 10mg
A light-emitting biomolecule that serves as a substrate for luciferases or constituent of photoproteins oxidation to coelenteramide is accompanied by emission of blue light (emission maximum 460-470 nm) used in BRET studies and to detect changes in calcium level and redox status
Cayman Chemical 11-deoxy ProstaglndIn F2 5mg
A substrate for the synthesis of RNA during the transcription process and the synthesis of DNA during DNA replication participates in G-protein-related signal transduction where it is converted to GDP through the action of GTPases
Cayman Chemical 1113 14dIhydro15keto Pro 50ug
An M1 muscarinic acetylcholine receptor antagonist (Ki 0.59 nM in rat brain membranes) selective for M1 receptors over the serotonin transporter (Ki 5150 nM) binds to the dopamine transporter and inhibits dopamine reuptake (Kis 237 and 130 nM respectively) inhibits acid sphingomyelinase by 87 at 10 mM
Cayman Chemical DNA Base ExcIsIonPath 50mg
Expected metabolite of JWH 081 that would be detectable both in serum and in urine
Cayman Chemical ProstaglndIn F1 10mg
An inhibitor of the hedgehog signaling pathway (IC50s 500-700 nM) induces a variety of birth defects in vivo reduces lipid accumulation and PPARY and C/EBPa gene expression in 3T3-L1 adipocytes in vitro
Cayman Chemical 1113 14dIhydro15keto Pro 100ug
A potential metabolite produced during metabolism of AB-CHMINACA in vivo intended for forensic and research applications
Cayman Chemical GIrard Reagent P 10g
An internal standard for the quantification of myristic acid by GC- or LC-MS
Sigma Aldrich Fine Chemicals Biosciences MCF10A CELLS PTEN
This cell line corresponds to ATCC Catalog No. CRL-10317.
