Oligonucleotides
MEDCHEMEXPRESS LLC GAPDH Human HEK293 100ug | 100ug
The GAPDH protein has dual roles in glycolysis and nuclear function It also affects the organization and assembly of the cytoskeleton and promotes the association of microtubules and membranes GAPDH Protein Human (HEK293 His) is the recombinant human-derived GAPDH protein expressed by HEK293 with N-6 His labeled tag
MEDCHEMEXPRESS LLC Transferrin R2 Mous 10ug | 10ug
The transferrin R2 protein is a key player in iron-independent cellular uptake of transferrin-bound iron underscoring its role in delicate iron metabolism Among other things it may have crucial effects on liver cell function and red blood cell differentiation Transferrin R2 Protein Mouse (HEK293 mFc) is the recombinant mouse-derived Transferrin R2 protein expressed by HEK293 with N-mFc labeled tag
Cellecta Inc SUPPLEMENTARY PRIMER SET
Supplementary Primer Set for LNGS-120 (12 Additional Index Primers)
![ABclonal Technology [KO Validated] Bax Rabbit pAb](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000135710.jpg-250.jpg)
ABclonal Technology [KO Validated] Bax Rabbit pAb
BAX (BCL2 Associated X) is a pro-apoptotic member of the BCL2 protein family, crucial in regulating apoptosis. It contains four Bcl-2 homology (BH1–BH4) domains and a C-terminal transmembrane domain. In healthy cells, BAX remains in the cytoplasm via interaction with anti-apoptotic proteins like BCL2L1 (Bcl-xL). Upon apoptotic stimuli, BAX undergoes a conformational change and translocates to the outer mitochondrial membrane, where it promotes apoptosis through two main mechanisms: interacting with the voltage-dependent anion channel (VDAC) to release cytochrome c, or forming oligomeric pores that permeabilize the membrane. Released cytochrome c activates caspase-3, triggering cell death. BAX is also a direct transcriptional target of p53 and plays a role in p53-mediated apoptosis, with p53 both regulating its expression and interacting with BAX to enhance its activity.
ABclonal Technology RALA Rabbit pAb
The product of this gene belongs to the small GTPase superfamily, Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that shares about 50% similarity with other ras proteins.
ABclonal Technology MDM2 Rabbit pAb
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
ABclonal Technology SEC14L2 Rabbit pAb
This gene encodes a cytosolic protein which belongs to a family of lipid-binding proteins including Sec14p, alpha-tocopherol transfer protein, and cellular retinol-binding protein. The encoded protein stimulates squalene monooxygenase which is a downstream enzyme in the cholesterol biosynthetic pathway. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
ABclonal Technology AFTMag Quick Gel DNA Extraction Kit (Prepackaged)
This kit uses magnetic bead-based technology for nucleic acid purification. It utilizes functional groups on magnetic beads to enrich nucleic acids from agarose gel onto the bead surface.The beads are then washed to remove impurities, and then separate magnetic beads with magnetic separation device, so as to quickly separate and purify DNA from samples. The whole process does not require the use of phenol, chloroform and β-merphytoethanol,, safe and non-toxic, and the use of paramagnetic magnetic beads, suitable for high-throughput automated extraction.
ABclonal Technology RK21625-5uleach Unique Dual I
ABclonal s Unique Dual Index for Illumina products contain universal truncated adapters and Unique Dual Index (UDI) primers for sample preparation for Next Generation Sequencing on Illumina sequencing Set B (CAT NO RK21625) provides 48 unique primer pairs (UDI Primers 49-96) All sets include 15 M truncated adapters along with the listed primers The sample index length is 8 nucleotides
ABclonal Technology MCT4/SLC16A3 Rabbit pAb
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1, MIM 600682) and MCT2 (SLC16A7, MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).
ABclonal Technology Oligo d(T)23VN (50 μM)
Oligo d(T)23VN is used for the priming and sequencing of mRNA adjacent to the 3-poly A tail. V equal A or G or C N equal A or G or C or T Reconstitute with water.
ABclonal Technology Damaged DNA Repair Enzymes II
FFPE refers to formalin-fixed paraffin-embedded samples, in which DNA is severely damaged. Damaged DNA Repair Enzymes II is an optimized enzyme mixture primarily used to repair FFPE sample DNA, thereby obtaining high-quality sequencing data.