Oligonucleotides
ATCC Big-Six Escherichia coli Genomic DNA Panel (MP-10) - six non-O157 STEC genomic DNA preparations
Big-Six Escherichia coli Genomic DNA Panel (MP-10) is a quality-control panel containing purified genomic DNA preparations from the six major non-O157 Shiga toxin-producing Escherichia coli (STEC) serogroups. The panel is intended for assay development, validation, and food-testing quality-control workflows.
- Contains purified genomic DNA from serogroups O26, O45, O103, O111, O121, and O145.
- Provides material for assay development, validation, and quality control.
- Components include genomic DNA preparations derived from representative strains of each serogroup.
- For laboratory research use only; not for human or diagnostic use.
- Component genomic DNAs are listed at biosafety level 1 on their individual product pages.
Cayman Chemical 1113 14dIhydro15keto Pro 50ug
A metabolite of PGD2; appears in plasma of normal males within 10 minutes of tritiated PGD2 infusion or inhalation
Cayman Chemical 1a 1b-dihomo Prostaglandin F2
A theoretical product of adrenic acid in the COX pathway; primarily produced in renal medulla where adrenic acid is selectively distributed
Cayman Chemical 17R 18S-EpETE 25ug
An EPA metabolite and activator of KCa1.1/BK channels; increases the potassium current amplitude by 15-fold in isolated rat cerebral artery VSMCs at 50 nM; has negative chronotropic effects in NRCMs (EC50 = ~1-2 nM) and prevents calcium-induced increases in NRCM spontaneous beating
ABclonal Technology AFTMag Quick Plant Leaf DNA Extraction Kit
This kit is a nucleic acid extraction kit based on magnetic beads. The main principle involves using functional groups on the surface of the magnetic beads to enrich nucleic acids from the sample lysate onto the surface of the beads. The beads are then washed to remove proteins and other impurities. Then, a magnetic separation device is used to isolate the beads, allowing for rapid separation and purification of nucleic acids. The entire process does not require the use of organic reagents such as phenol, chloroform, or β-mercaptoethanol, making it safe and non-toxic. The use of paramagnetic magnetic beads is suitable for high-throughput automated extraction.
Abcam Methylated Control DNA Kit.
Methylated Control DNA Kit.
The product is subject to the following: Abcam Restricted Use Statement
![ABclonal Technology [KO Validated] Bax Rabbit pAb](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000138792.jpg-250.jpg)
ABclonal Technology [KO Validated] Bax Rabbit pAb
BAX (BCL2 Associated X) is a pro-apoptotic member of the BCL2 protein family, crucial in regulating apoptosis. It contains four Bcl-2 homology (BH1–BH4) domains and a C-terminal transmembrane domain. In healthy cells, BAX remains in the cytoplasm via interaction with anti-apoptotic proteins like BCL2L1 (Bcl-xL). Upon apoptotic stimuli, BAX undergoes a conformational change and translocates to the outer mitochondrial membrane, where it promotes apoptosis through two main mechanisms: interacting with the voltage-dependent anion channel (VDAC) to release cytochrome c, or forming oligomeric pores that permeabilize the membrane. Released cytochrome c activates caspase-3, triggering cell death. BAX is also a direct transcriptional target of p53 and plays a role in p53-mediated apoptosis, with p53 both regulating its expression and interacting with BAX to enhance its activity.
ABclonal Technology CD43 Rabbit mAb
This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells and is found on the surface of thymocytes T lymphocytes monocytes granulocytes and some B lymphocytes It contains a mucin-like extracellular domain a transmembrane region and a carboxy-terminal intracellular region The extracellular domain has a high proportion of serine and threonine residues allowing extensive O-glycosylation and has one potential N-glycosylation site while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals Different glycoforms of this protein have been described In stimulated immune cells proteolytic cleavage of the extracellular domain occurs in some cell types releasing a soluble extracellular fragment Defects in expression of this gene are associated with Wiskott-Aldrich syndrome