Oligonucleotides
Abcam EI1, EZH2 inhibitor, 10MG
MW 390.5 Da. Potent (IC₅₀ = 15 nM for wild-type enzyme; 13 nM for Y641F mutant enzyme) EZH2 inhibitor. Selective versus EZH1 (142-fold). Highly selective (>10,000-fold) against a panel of 10 other human methyltransferases. Inhibits cellular H3K27 methylation and activates Ezh2 target gene p16 expression in diffuse large B-cell lymphoma cells (DLBLC). Selectively inhibits growth and promotes cell cycle arrest and apoptosis of DLBLC cells with Y641 EZH2 mutations.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences TRI ReagentR for DNA RNA a
TRI reagent(R) also known as TRIzol is a monophasic SOLUTIONon of phenol and guanidinium isothiocyanate. It has a potential to simultaneously solubilize biological material and denatures protein. It is widely used for deproteinizing RNA. This improved version of the single-step total RNA isolation reagent developed by Chomczynski allows a quick economical and efficient isolation of total RNA from different biological samples. This product is pure (A260/A280 ~1.8) and can be directly used in Northern blotting. Simultaneous isolation of DNA RNA and proteins is also possible. 1 mL is sufficient for the extraction of 100 mg tissue or 107 cells.
Electron Microscopy Sciences Polyview Page Storage Box
Archival quality black binder is made of rigid polypropylene for safe storage for prints, slides, CDs or negative pages. It features 1" O-rings, positive snap locks and a flexible hinge. It is super tough and dust and moisture resistant. Capacity: (1" O-ring) 50 negative pages, 35 print pages, 18 slide pages or 10 CD pages.
MOLECULAR DEPOT LLC Protein DNA Crystal - 48/1 mL
Crystallization Screen for Protein DNA Complexes is a crystallization screen consisting of 48 unique crystallization reagents that were proven to be successful in crystallizing protein-DNA complexes These 48 reagents were formulated after analyzing over 7000 published protein-DNA crystallization conditions and formulating unique reagents that included critical components for the growth of protein-DNA crystals such as the presence of polyamines PEG of various molecular weights divalent ions various salts reducing agents and other additives For in vitro research use only
BIOHIPPO AAV-c-Fos-EYFP-WPRE-hGH-polyA
Recombinant adeno associated virus expressing EYFP under the c-Fos promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Medchemexpress LLC GAPDH Human HEK293 100ug | 100ug
The GAPDH protein has dual roles in glycolysis and nuclear function It also affects the organization and assembly of the cytoskeleton and promotes the association of microtubules and membranes GAPDH Protein Human (HEK293 His) is the recombinant human-derived GAPDH protein expressed by HEK293 with N-6 His labeled tag
ABclonal Technology POU2F1/OCT1 Rabbit pAb
The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.
BIOHIPPO AAV-D1-EYFP-WPRE-bGH-polyA
Recombinant adeno associated virus expressing EYFP under the D1 promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
BIOHIPPO AAV-CAG-H2B-tdTomato-WPRE-hGH-polyA
Recombinant adeno associated virus expressing TDTOMATO H2B-tdTomato under the CAG promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Cayman Chemical MOG PeptIdehumnbovIn 10mg
An endogenous myelin sheath peptide; reduces cortical and striatal infarct volumes, decreases sensorimotor impairments in tube- and corner turn tests, increases time spent investigating novel odors, and increases the duration of cage mate-directed calls in female, but not male, mice in a MCAO-induced mouse model of ischemic stroke when coupled to HLA-DR2
ABclonal Technology MDM2 Rabbit pAb
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
American Research Products Inc Pig Interferon b IFN b IFNB E
Pig Interferon b IFN-b/IFNB ELISA Kit from CUSABIO Detection Range 50 pg/mL-2000 pg/mL Sensitivity 25 pg/mL Sample serum plasma tissue homogenates cell lysates Method Sandwich
Medchemexpress LLC Von Hippel-Lindau protein (human) | >90.0% | 10 UG
Recombinant full-length human von Hippel-Lindau (VHL) protein with an N-terminal 6xHis tag, supplied as a lyophilized powder for research applications. The protein corresponds to residues M1-D213 (Accession P40337), is expressed in E. coli, and is provided with low endotoxin and high purity suitable for biochemical and binding assays.
- Source organism: human.
- Sequence length: full length (M1-D213).
- Tag: N-terminal 6xHis for affinity purification.
- Expression system: E. coli.
- Purity: >90.0% by reducing SDS-PAGE.
- Molecular weight: ~34 kDa.
- Endotoxin: <1 EU/μg.
- Appearance and formulation: lyophilized powder with trehalose-containing buffer.
- Storage and reconstitution: store lyophilized at -20°C; do not reconstitute below 100 μg/mL in ddH2O; freeze aliquots for long-term storage.
