Oligonucleotides
Revvity Health Sciences Inc NEXTFLEX Unique Dual Index Barcodes (8NT index, 1-8)
NEXTFLEX Unique Dual Index Barcodes (8NT index, 1-8)
New England Biolabs, Inc. NEBNext Enzymatic 5hmC-seq Kit 24 rxns
The NEBNext Enzymatic 5hmC-seq Kit specifically detects 5hmC sites. The kit includes NEBNext Ultra II library prep reagents, and 5hmC is detected using a two-step enzymatic conversion workflow that minimizes damage to DNA and allows discrimination of 5hmC from both cytosine and 5mC after Illumina sequencing. E5hmC-seq data can also be subtracted from EM-seq data, allowing determination of the precise location of individual 5mC and 5hmC sites. The kit includes the E5hmC-seq adaptor and index primers are supplied separately.
New England Biolabs, Inc. E. coli tRNA - 1 mg
E. coli tRNA is a mix of tRNAs isolated from E. coli and purified by chromatography to remove contaminating proteins, including nucleases, as well as other nucleic acids. This tRNA formulation sustains translation in E. coli-based in vitro protein synthesis reactions (also referred to as cell-free protein synthesis or CFPS). It is also suited for molecular biology applications that require highly pure and active prokaryotic tRNA.
- Highly active tRNA for in vitro translation
- Purified by chromatography, no organic solvents
- Highly pure with undetectable levels of nucleases and proteases
- Manufactured with reduced environmental impact
- Compatible with a variety of molecular biology workflows
Medchemexpress LLC ODN 1018 | 937402-51-2 | DNA, d(P-thio)(T-G-A-C-T-G-T-G-A-A-C-G-T-T-C-G-A-G-A-T-G-A) | 5 MG
ODN 1018 is a TLR9 agonist and immune modulator. It exhibits adjuvant activity and augments CD8+ T cell responses when used with LNP-encapsulated OVA peptides. ODN 1018 can trigger sustained suppression of allergic airway inflammation and can be used for research into allergic asthma and systemic lupus erythematosus.
- TLR9 agonist and immune modulator
- Exhibits adjuvant activity
- Augments CD8+ T cell responses with LNP-encapsulated OVA peptides
- Triggers sustained suppression of allergic airway inflammation
- Can be used for the research of allergic asthma and systemic lupus erythematosus
Cayman Chemical GW 4869 hydrochloride hydrat
An inhibitor of neutral sphingomyelinase (IC50 = 1 μM); selective for neutral sphingomyelinase over acid sphingomyelinase at concentrations up to 150 μM as well as B. cereus PC-PLC, human lyso-PAF PLC, and bovine PP2A at 10 μM; inhibits TNF-α-induced sphingomyelin hydrolysis and TNF-α-induced cell death in MCF-7 cells; reduces the inhibitory effects of OxPAPC and KOdiA-PE on LPS-induction of IL-8 in human aortic endothelial cells; reverses hypoxia-induced pulmonary vasoconstriction in rats at 1 mg/kg
AdipoGen iODN (inhibitory ODN) 2088 Endotoxin-free (sterile)
iODN (inhibitory ODN) 2088 Endotoxin-free (sterile), AdipoGen Life Sciences. Chemical. MW: 4,887g/mol. In recent years several groups have studied the sequence requirements, specificity, signaling pathways and kinetics of the TLR (Toll-like receptor) 9 suppression by inhibitory oligonucleotide motifs, which led to a class of novel inhibitory oligonucleotide (iODNs), that is independent of the previously thought species preference. Subsequently it has been discovered that telomeric DNA repeats (TTAGGG)n can block immune activation by CpG-ODNs. Short, 11-15 base long oligonucleotides were synthesized that were capable of potently inhibiting CpG-stimulation.
CPC Scientific 5FAM-Gly-Tyr-Ile-Tyr-Gly-Ser-Phe-Lys-Lys-OH (trifluoroacetate salt) 0.5MG
ONE-LETTER SEQUENCE: 5FAM-GYIYGSFKKMOLECULAR FORMULA: C73H85N11O19MOLECULAR WEIGHT:1420.6STORAGE CONDITIONS: -20 5CRESEARCH AREA: Protein Kinases and Phosphatases
CPC Scientific 5FAM-Gly-Gly-Gly-Pro-Ala-Thr-Pro-Lys-Lys-Ala-Lys-Lys-Leu-OH (trifluoroacetate salt) 1MG
ONE-LETTER SEQUENCE: 5FAM-GGGPATPKKAKKLMOLECULAR FORMULA: C77H111N17O21MOLECULAR WEIGHT:1610.8STORAGE CONDITIONS: -20 5CRESEARCH AREA: Protein Kinases and Phosphatases
CPC Scientific 5FAM-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-Lys-NH2 (trifluoroacetate salt) 0.5MG
ONE-LETTER SEQUENCE: 5FAM-GPWLEEEEEAYGWMDFK-NH2MOLECULAR FORMULA: C119H141N21O36S1MOLECULAR WEIGHT:2473.6STORAGE CONDITIONS: -20 5CRESEARCH AREA: Protein Kinases and Phosphatases
CPC Scientific 5FAM-Lys-Lys-Arg-Lys-Ser-Ser-Leu-Arg-Arg-Trp-Ser-Pro-Leu-Thr-Pro-Arg-Gln-Met-Ser-Phe-Asp-Cys-NH2 (trifluoroacetate salt) 1MG
ONE-LETTER SEQUENCE: 5FAM-KKRKSSLRRWSPLTPRQMSFDC-NH2MOLECULAR FORMULA: C138H206N40O36S2MOLECULAR WEIGHT:3065.6STORAGE CONDITIONS: -20 5CRESEARCH AREA: Protein Kinases and Phosphatases