Oligonucleotides
Medchemexpress LLC Odn 1826 | 202668-42-6 | 10MG
ODN 1826 is a class B CpG oligodeoxynucleotide that functions as a mouse TLR9 agonist. It is a synthetic, single-stranded 20-mer with a full phosphorothioate backbone and unmethylated CpG motifs, used to activate B cells and induce pro-inflammatory cytokines in preclinical mouse studies.
- Synthetic 20-mer oligodeoxynucleotide with a phosphorothioate backbone
- Contains unmethylated CpG motifs that activate mouse TLR9
- Potent stimulator of B cells and pro-inflammatory cytokine production
- Commonly used as a vaccine adjuvant or immunostimulant in mouse models
- Nuclease resistant for improved in vivo stability
- High purity (>98% HPLC) available and lot-tested for biological activity
Medchemexpress LLC GAPDH Human HEK293 5ug | 5ug
The GAPDH protein has dual roles in glycolysis and nuclear function It also affects the organization and assembly of the cytoskeleton and promotes the association of microtubules and membranes GAPDH Protein Human (HEK293 His) is the recombinant human-derived GAPDH protein expressed by HEK293 with N-6 His labeled tag
Biotium DNA Ligase 1(1A9), Biotin conjugate, 0.1mg/mL
DNA Ligase I maintains the major DNA Ligase activity in proliferating cells by joining Okazaki fragments during lagging strand DNA replication. Human DNA Ligase I also has an essential role in DNA repair pathways, where it catalyzes the formation of phosphodiester bonds between adjacent 5' phosphoryl and 3' hydroxy termini at single breaks in duplex DNA molecules. In addition, DNA Ligase I plays a role in sealing nicks during excision repair. Similar to other DNA ligases, DNA Ligase I is built around a common catalytic core. Increased levels of DNA Ligase I are found in human tumors, as compared to benign tissues, as well as in peripheral blood lymphocytes. DNA Ligase I activity is altered in the chromosomal breakage deficit Bloom's syndrome (BS). Individuals with BS either have decreased levels of abnormally thermolabile DNA Ligase I or possess a dimeric form of this enzyme. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. C
Biosurface Technologies Corp 4-Channel Aluminum Drip Flow Biofilm Reactor, Low-Shear Laboratory Biofilm Growth Device, BioSurface Technologies Corporation.
"The Model DFR 110 Drip Flow Biofilm Reactor® consists of four (4) or six (6) parallel test channels, each capable of holding one (1) standard glass microscope slide-sized coupon, or a length of catheter or stint (after custom modification upon request). Growth media is provided by dripping over the coupon or catheter surface. Biofilm growth conditions provide low shear, and short residence time (2 minutes). Catheter and stent studies can also utilize the alternate end media port to provide flow within the catheter or stent. Media flows via gravity to provide a very low shear condition.The Drip Flow Biofilm Reactor® is ideal for microsensor monitoring, general biofilm studies, biofilm cryosectioning samples, high biomass production, dental and medical material evaluations, and indwelling medical device evaluations.ASTM E2647 is a standardized method developed for the Drip Flow Biofilm Reactor®.
Cayman Chemical NotogInsenosIde R1 10mg
A saponin; decreases serum total cholesterol, triacylglycerol, and oxLDL levels, as well as reduces atherosclerotic lesion area and lipid deposition in the aortic root of ApoE-/- mice fed a Western diet at 25 mg/kg per day for 8 weeks; inhibits apoptosis of hippocampal neurons and reduces infarct size in a rat model of cerebral ischemia-reperfusion injury induced by bilateral common carotid artery occlusion at 100 mg/kg; decreases colonic NF-ĸB and MPO activities and TNF-α and IL-6 levels, as well as reduces colonic shortening, tissue damage, and inflammatory cell infiltration in a DSS-induced mouse model of colitis at 25 mg/kg per day for 7 days
Medchemexpress LLC Anti-CXCR3 GPR9 CD18 5mg | 5mg
Anti-CXCR3/GPR9/CD183 Antibody is a human-derived antibody expressed in CHO targeting CXCR3/GPR9/CD183 The Anti-CXCR3/GPR9/CD183 Antibody has a huIgG1 heavy chain and a hu light chain with a predicted molecular weight (MW) of 150 kDa For the isotype control of Anti-CXCR3/GPR9/CD183 Antibody please refer to Human IgG1 kappa Isotype Control (HY-P99001)
Sino Biological Human GAPDH qPCR Primer Pair
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Genscript Corporation VEGF R2/KDRBiotin mFc Chimer
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA VEGFB and PGF and plays an essential role in the development of embryonic vasculature the regulation of angiogenesis cell survival cell migration macrophage function chemotaxis and cancer cell invasion The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis
Biotium SOX9 / SRY-box 9(SOX9/2287R), Biotin conjugate, 0.1mg/mL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19, 000, full-length human proteins. Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Nucleus (Potential). Campomelic dysplasia (CMD1) : Rare, often lethal, dominantly inherited, congenital osteo-chondrodysplasia, associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones, unusually small scapulae, deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate, micrognathia, flat face and hypertelorism are common. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and phot