Oligonucleotides
Enzo Life Sciences Oligomycin A (25mg). CAS: 579-13-5
Inhibits mitochondrial ATPases (F1F0). Stimulates lysosome acidification due to shunting of membrane potential. Induces apoptosis in a variety of cell types. Induces autophagy in the IPLB-LdFB insect cell line. Purity: ≥97% (HPLC, TLC). Solubility: Soluble in DMSO (300mg/ml), 100% ethanol (200mg/ml) or acetone (800mg/ml). Long Term Storage: -20°C.
Biotium SOX9 / SRY-box 9(SOX9/3141R), 1mg/mL
Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye col
Cayman Chemical CXCR3 ntagonIst 6c 1mg
A CXCR3 antagonist; inhibits calcium mobilization induced by CXCL11 in HEK293 cells expressing the human receptor (IC50 = 0.06 µM); selective for CXCR3 over a panel of 14 human G protein-coupled receptors at 10 µM; inhibits CXCR3-mediated migration of isolated human T cells (IC50 = ~100 nM)
Revvity Health Sciences Inc NEXTFLEX 16S V1-V3 rRNA Amplicon-seq Kits, Barcodes 1-96
NEXTFLEX 16S V1-V3 rRNA Amplicon-seq Kits, Barcodes 1-96
Biotium pS2(TFF1/1091), CF488A conjugate, 0.1mg/mL
This antibody recognizes a polypeptide of 6.5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased
Eagle Biosciences Inc 293T Cell Residual DNA Fragment Analysis Detection Kit (qPCR
293T Cell Residual DNA Fragment Analysis Detection Kit (qPCR
Revvity Health Sciences Inc DOPlify Whole Genome Amplification V2 Kit
DOPlify Whole Genome Amplification V2 Kit
Genscript Corporation MSLN/Mesothelin296-580 hFc C
Mesothelin also known as MSLN is a protein that in humans is encoded by the MSLN gene Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF) Although it has been proposed that mesothelin may be involved in cell adhesion its biological function is not known A knockout mouse line that lacks mesothelin reproduces and develops normally
Cayman Chemical CXCR3 ntagonIst 6c 5mg
A CXCR3 antagonist; inhibits calcium mobilization induced by CXCL11 in HEK293 cells expressing the human receptor (IC50 = 0.06 µM); selective for CXCR3 over a panel of 14 human G protein-coupled receptors at 10 µM; inhibits CXCR3-mediated migration of isolated human T cells (IC50 = ~100 nM)
Biotium CD43 (T-Cell Marker)(SPN/3388), CF488A conjugate, 0.1mg/mL
Recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targe
Sigma Aldrich Fine Chemicals Biosciences Uracil DNA Glycosylase hea
Uracil-DNA Glycosylase heat-labile contains the equally named enzyme found in the marine bacterium BMTU 3346. Like the UNG from E. coli it hydrolyzes uracil-glycosidic bonds in single- or double-stranded DNA excising uracil and creating alkali-sensitive abasic sites in the DNA. These abasic sites can be hydrolyzed by endonuclease heat or alkali treatment. Depending on how the DNA is prepared Uracil-DNA Glycosylase can be used to achieve general site-specific or strand-specific U-DNA cleavage. This enzyme shows lower thermostability and is therefore easier to inactivate.Enzyme CharacteristicsThe BMTU 3346 enzyme is inactivated more quickly (2 minutes at 95C) than the corresponding enzyme from E. coli (10 minutes at 95C). It has also been reported that UNG from E. coli remains partially active leading to the degradation of the dU-containing PCR product. In contrast the heat-labile UNG does not degrade dU-PCR products within at least several hours of incubation at 2 to 8C. Theref
BIOHIPPO AAV-cTNT-iCre-IRES2-tdTamato-polyA
Recombinant adeno associated virus expressing iCre tdTomato under the cTNT promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
BIOHIPPO AAV-RAM-d2tTA-TRE-hM3D(Gq)-EYFP-WPRE-bGH-polyA
Recombinant adeno associated virus expressing d2TTA hM3D(Gq) fused to EYFP under the RAM TRE promoter with WPRE and hGH polyA elements. The Tet responsive configuration enables doxycycline controlled expression, providing precise chemogenetic control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.