Oligonucleotides
Abcam alpha-NETA, Fluorescent ChAT inhibitor, 25MG
MW 369.24 Da. alpha-NETA, Fluorescent ChAT inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam T0901317, L x R agonist, 10MG
MW 481.3 Da, Purity >99%. Potent, non-selective LXR agonist (EC₅₀ = 50 nM). Increases ABCA1 expression associated with cholesterol efflux regulation and HDL metabolism. Increases muscle expression of PPAR-δ. Shows antiobesogenic effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical PalmItIc ACD13CC2 labeled 10mg
A triacylglycerol reduces total cholesterol levels in both the plasma and aorta in a diet-induced hamster model of hypercholesterolemia
Cayman Chemical ANTIBODY SET2 10mg
An inhibitor of NLRP3 inflammasome activation inhibits ATP-induced IL-1B release by 98.3 in LPS-primed mouse BMDMs at 1 UM decreases paw swelling and mechanical hyperalgesia in a mouse model of gout induced by monosodium urate crystals at 3 and 10 mg/kg
Cayman Chemical PalmItIc AcId-13CC1 labeled 1g
A minor phase II metabolite of ( )-sitagliptin formed by N-carbamoyl glucuronidation has been found in rat and dog plasma
Cayman Chemical 1F-Fructofurnosylnystose 10mg
A metabolite of D-glutamate urine levels are increased in patients with nascent metabolic syndrome plasma levels are increased in patients with end-stage renal disease
Cayman Chemical O6-methylguanine-DNA Methyltr
A high-affinity ligand of A-FABP/aP2 (Ki 0 67 M) shown to antagonize the protein-protein interaction of A-FABP/aP2 with hormone sensitive lipase in cultured C8PA lipocytes presumably competes with fatty acids for functional binding in the ligand-binding cavity of A-FABP/aP2
Cayman Chemical TFF1 trefoil factor 1 or pS2
An alkaloid inhibits the growth of human A375 A431 A549 MES-SA and MCF-7 cells (IC50 3 nM for all) inhibits hypoxia-induced gene expression in an HRE reporter assay (IC50 8.7 nM) prevents lesion formation in TMV-infected tobacco plants at 500 Ug/ml inhibits protein synthesis by yeast and mammalian ribosomes
Cayman Chemical DNA MethyltrnsfRase 3a Mon 1ea
A CB2 receptor agonist and inverse agonist greater than 100-fold selective for the CB2 (Ki 15 nM) over the CB1 receptor (Ki 5000 nM) acts as an agonist at human CB2 receptors (EC50 118 nM) but an inverse agonist of rat and mouse CB2 receptors (EC50s 315 and 341 nM respectively) produces antinociception to thermal but not mechanical pain in rats
Cayman Chemical VHL LIgnd 1hydrochlorIde 25mg
An active metabolite of caffeine an adenosine A1 and A2 receptor antagonist (Kis 35 and 22 UM respectively) increases striatal cGMP and extracellular striatal dopamine levels and locomotor activity as well as inhibits motor depression induced by CPA or CGS 21680 in rats not habituated to caffeine at 30 mg/kg promotes wakefulness and increases locomotor activity and core temperature in narcoleptic transgenic mice without increasing behavioral anxiety
Cayman Chemical DNA MethyltrnsfRase 3a Mon 1ea
A CB2 receptor agonist and inverse agonist greater than 100-fold selective for the CB2 (Ki 15 nM) over the CB1 receptor (Ki 5000 nM) acts as an agonist at human CB2 receptors (EC50 118 nM) but an inverse agonist of rat and mouse CB2 receptors (EC50s 315 and 341 nM respectively) produces antinociception to thermal but not mechanical pain in rats
Cayman Chemical DNA MethyltrnsfRase 1 Monc 1ea
A CB2 receptor agonist selective for the CB2 over the CB1 receptor (Kis 658 and 10000 nM respectively) acts as an agonist at human rat and mouse CB2 receptors but shows greater activity at human CB2 (EC50 131 nM) than at rat and mouse CB2 receptors (EC50 785 and 2000 nM respectively) produces antinociception to thermal but not mechanical pain in rats
Cayman Chemical ZngIbrosIde R1 10mg
A PI3K inhibitor (IC50 1 nM) selective for PI3K over PI3Ka PI3KB and PI3KY (IC50s 10000 nM for all) as well as a panel of 192 additional kinases and a panel of 70 ion channels and transporters at 1 UM inhibits primary human B cell proliferation (IC50 0.2 nM) and memory T cell cytokine production (IC50s 0.2-1.5 nM) inhibits the differentiation of naïve isolated human T cells into Th1 Th2 or Th17 T helper cells inhibits the proliferation of JeKo-1 Mino Rec-1 and JVM-2 lymphoma cells (IC50s 50s 2-8 nM) reduces intratumoral phosphorylation of Akt and tumor growth in a Pfeiffer mouse xenograft model from 0.1-10 mg/kg reduces proteinuria lymphadenopathy and the severity of skin lesions in an MRL/MpJ-Fas lpr mouse model of spontaneous SLE at 3 mg/kg reduces salivary levels of TNFSF13B and plasma levels of anti-SSA and anti-SSB autoantibodies in a NOD.ShiLtJ mouse model of Sjögrens syndrome
Cayman Chemical ANTIBODY SET2 50mg
An analytical reference standard that is structurally similar to known phytocannabinoids intended for research and forensic applications
Cayman Chemical CelecoxIb Carylc ACD Acy 1mg
An antipsychotic that binds D2-like receptors preferentially over D1-like receptors (Kis 0 06 0 3 and 0 15 nM for D2 D3 and D4 respectively) also binds 1 and 2 receptors (Kis 8 4 and 9 6 nM respectively) and activates the 5-HT1A receptor (IC50 34 nM)