Cell Lines and Cell Cultures
American Research Products Inc Canine connectiVe tissue growt
Canine connectiVe tissue growth factor CTGF ELISA Kit from CUSABIO Detection Range 62 5 pg/mL-4000 pg/mL Sensitivity 15 6 pg/mL Sample serum plasma tissue homogenates Method Sandwich
Eurofins Discoverx Ready-to-Assay MC5 Melanocortin Receptor Frozen Cells, 2 Vials of Cells. (HTS155RTA)
The Ready-to-Assay MC5 Melanocortin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. α-MSH) based activation of MC5R GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses MC5R alongside exogenous levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of MC5R, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx PathHunter CHO-K1 mGALR1 β-Arrestin Cell Pool, 2 vials. (93-0603P2)
The PathHunter mGALR1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. galanin) based activation of mGALR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mGALR1 and EA-tagged β-Arrestin-2. Activation of mGALR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable cell pool is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Paraffin Tissue Section - Arrhythmia, infarct: Heart Atrium, left, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from single human diseased sample. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Eurofins Discoverx PathHunter CHO-K1 BAI1 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0545C2)
The PathHunter BAI1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of BAI1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged BAI1 and EA-tagged β-Arrestin-2. Activation of BAI1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Cayman Chemical al-trns RetInal 1g
A natural retinoid that associates with CRBP-I and CRBP-II (Kds = 50 and 90 nM, respectively), which are involved in the intracellular transport of retinol; an intermediate of the phototransduction pathway of photoreceptors; can form toxic conjugates with proteins and lipids, leading to degeneration of the retina
Genscript Corporation CHO-K1/ADRA1B Stable Cell Line
Recombinant CHO-K1 cells stably overexpress human adrenoceptor alpha 1B (ADRA1B) on the surface and contain high levels of G protein G q to couple with the receptor in downstream signaling pathways
Montana Molecular Human Melanocortin 1 Receptor (MC1R) Big Sky BacMam, 15mL
Human Melanocortin 1 Receptor (MC1R) packaged in Big Sky BacMam for robust expression in mammalian cells. BacMam packaging provides efficient transduction in most cell types - including uniform and near 100% efficiency in HEK293 cells as well as expression in primary or iPSC-derived cells. BacMam expression is easily titrateable to suit your experimental needs.
Cayman Chemical 9-cIs RetInal 5mg
A natural retinoid that is produced by oxidation of 9-cis retinol by cRDH; binds to CRBP-I, CRBP-II, and CRALBP (Kds = 8, 5, and 53.3 nM, respectively); inhibits differentiation of RCJ C5.18 chondrogenic cells into cartilage in vitro (IC50 = 8 nM); it rescues cone ERG responses in Irbp-/- mice (0.375 mg)
ATCC Pfizer Pneumococcal polysaccharide powder Type 3 (d3) 200mg
Purified pneumococcal polysaccharide type 3 is manufactured by Pfizer, Inc., for small-quantity distribution by ATCC. The pneumococcal powder type 3 is a component of the current 13-valent vaccine against Streptococcus pneumoniae. The pneumococcal polysaccharide type 3 can be used to assay for type-specific antibodies, research immune responses, and study immunodeficiencies.
Montana Molecular Human Succinate Receptor (SUCNR1, SUCR1) BacMam, 30mL
Use this assay to express the human Succinate receptor in your cells of interest. BacMam packaging provides efficient transduction in most cell types - including uniform and near 100% efficiency in HEK293 cells as well as expression in primary or iPSC-derived cells. Importantly, BacMam expression is easily titrateable to suit your experimental needs. This tool can be co-expressed with Montana Molecular's assays for cAMP to investigate signaling dynamics at the SUCNR1 receptor.
Amsbio LLC TLR8/NF-kB Leeporter™ Luciferase Reporter-HEK293 Cell Line
TLR8/NF-kB Leeporter™ Luciferase Reporter-HEK293 Cell Line
Eurofins Discoverx PathHunter CHO-K1 GHSR1b β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0354C2A)
The PathHunter GHSR1b cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. ghrelin) based activation of GHSR1b GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GHSR1b and EA-tagged β-Arrestin-2. Activation of GHSR1b stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter U2OS SSTR5 β-Arrestin Cell Line, 2 vials. (93-0402C3)
The PathHunter SSTR5 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. somatostatin) based activation of SSTR5 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged SSTR5 and EA-tagged β-Arrestin-2. Activation of SSTR5 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Paraffin Tissue Section - Human Colon Tumor, 5 sides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from a single human tumor. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.