General Cell Lines and Cell Cultures
Amsbio LLC eLuCidate™ HEK 293, SRF-RE Reporter Cell Line
eLuCidate™ HEK 293 SRF-RE Reporter Cell Line
Genscript Corporation CD47 hFc ChimeraBiotin Avi
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRP ) CD-47 acts as a don t eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers
Genscript Corporation CHO-K1/EDNRB Stable Cell Line
In mammals the endothelin (ET) family comprises three endogenous isoforms ET-1 ET-2 and ET-3 These endothelium-derived peptides perform their functions via two endothelin receptors classified as EDNRA and EDNRB EDNRB receptors present on the endothelial cells lining the vessel wall and play a role in the release of endothelium-derived relaxing factors such as nitric oxide (NO) and prostanoids and in removing ET from the circulation