General Cell Lines and Cell Cultures
ATCC UACC-812; Breast Ductal Carcinoma; Human (Homo sapiens)
UACC-812 is a cell line exhibiting epithelial-like morphology that was isolated from the mammary gland of a White, 43-year-old, female patient with ductal carcinoma. This cell line was deposited by A Liebovitz, J Trent, and can be used in cancer research.
Biolegend Alexa FluorR 700 anti-human TC
Alexa Fluor 700 anti-human TCR Vα7.2 [3C10]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 100 tests
Bioss Androgen receptor/AR3 specific
Androgen receptor (AR3 specific) Primary Antibody Unconjugated Host Species Rabbit Target Species Human Clonality Monoclonal Applications WB IHC-P IHC-F IF RecombinantConcentration 1ug/ul Size 100 ul Storage Buffer 10mM phosphate buffered saline(pH 7 4) with 150mM sodium chloride 0 05% BSA 0 02% sodium azide and 50% glycerol
Eurofins Discoverx ChemiScreen SUCNR1/GPR91 Succinate Receptor Stable Cell Line, 2 vials. (HTS241C)
The ChemiScreen SUCNR1/GPR91 Succinate Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. succinate) based activation of SUCNR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses SUCNR1 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of SUCNR1, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx Ready-to-Assay MCH1 Melanin-Concentrating Hormone Receptor Frozen Cells, 2 Vials of Cells. (HTS025RTA)
The Ready-to-Assay MCH1 Melanin-concentrating Hormone Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. MCH) based activation of MCHR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses MCHR1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of MCHR1, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx PathHunter HEK 293 GPR150 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0375C1A)
The PathHunter GPR150 (AXOR70) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR150 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR150 and EA-tagged β-Arrestin-2. Activation of GPR150 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter U2OS MC3R β-Arrestin Cell Line, 2 vials. (93-0984C3)
The PathHunter MC3R cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. α-MSH) based activation of MC3R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MC3R and EA-tagged β-Arrestin-2. Activation of MC3R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter LTB4R Total Internalization U2OS Cell Line, 2 vials. (93-0810C3)
The PathHunter LTB4R Total Internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of LTB4R via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged LTB4R and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the LTB4R receptor to the early endosome leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx ChemiScreen D5 Dopamine Receptor Membrane Preparation, 1 vial. (HTS129M)
The ChemiScreen D5 Dopamine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of DRD5 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx BDKRB1 Gq Calcium Signaling Cell-Based Assay Kit (CHO-K1)
The BDKRB1 Gq Stable Cell Line Calcium Signaling Assay (CHO-K1) contains a stable clonal cell line used to measure BDKRB1 (GPCR) activation via an increase in intracellular calcium. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Medchemexpress LLC CD47 protein, rat, recombinant (HEK293), Fc-tagged | 95.0% | 5 UG
Recombinant rat CD47 extracellular domain produced in HEK293 mammalian cells and supplied as an Fc-fusion protein. Designed for in vitro applications including binding assays, ELISA, and cell signaling studies. Available in microgram quantities with estimated purity ~95.0%.
- Mammalian expression ensures native glycosylation and folding.
- Fc fusion facilitates detection, purification, and immobilization.
- Estimated purity of 95.0% supports reliable assay performance.
- Available in small microgram pack sizes for assay optimization.
- Suitable for binding assays, ELISA, and receptor-ligand interaction studies.
Eurofins Discoverx RBL-2H3 MRGPRX1 Gq Cell Line, 2 vials. (95-1019C11)
The MRGPRX1 Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. BAM (8-22)) based activation of MRGPRX1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses MRGPRX1, a naturally Gq coupled GPCR. Upon activation of MRGPRX1, the resulting calcium activity can be fluorescently assayed using the Calcium No WashPLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx ChemiBrite DP Prostanoid Receptor Stable Cell Line, 2 vials. (HTS091L)
The ChemiBrite DP Prostanoid Receptor cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. prostaglandin D2) based activation of PTGDR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses PTGDR alongside exogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. ChemiBrite cells also express a clytin variant, allowing for luminescent as well as fluorescent signal detection. Upon activation of PTGDR, the resulting calcium activity can be assayed in either detection mode. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.