General Cell Lines and Cell Cultures
ATCC Dengue virus 4; Strain: H241; Tissue culture adapted
Dengue virus type 4 strain H241 is propagated in rhesus monkey kidney cells (RhMkK) (ATCC CCL-7.1). This product was derived by adaptation of suckling mouse–passaged H241 (ATCC VR-217) to RhMkK tissue culture (ATCC CCL-7.1). This product has applications in vector-borne disease research.
Eurofins Discoverx Ready-to-Assay 5-HT2B Serotonin Receptor Frozen Cells, 2 Vials of Cells. (HTS109RTA)
The Ready-to-Assay 5-HT2B Serotonin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. serotonin/5-HT) based activation of HTR2B GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses HTR2B alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of HTR2B, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC DMEM: F-12 Medium
DMEM: F-12 Medium contains 2.5 mM L-glutamine, 15 mM HEPES, 0.5 mM sodium pyruvate, and 1200 mg/L sodium bicarbonate. It has applications for cell culture, cell growth, and viability.
ATCC Mycoplasma hominis; Quantitative CRM; genomic DNA
Quantified genomic DNA isolated from Mycoplasma hominis strain [LBD-4] (ATCC 27545). This quantitative external control was produced under an ISO 17034 accredited process for use in testing and calibration in ISO 17025 accredited laboratories, inclusivity/exclusivity testing, establishing limits of detection, verification or comparison of test methods, and other molecular applications.
ATCC Pfizer Pneumococcal polysaccharide powder Type 12 (d12F) 10mg
Purified pneumococcal polysaccharide type 12F is manufactured by Pfizer, Inc., for small-quantity distribution by ATCC. The pneumococcal polysaccharide type 12F can be used to assay for type-specific antibodies, research immune responses, and study immunodeficiencies.
ATCC LN-18; Glioblastoma; Human (Homo sapiens)
LN-18 is a cell line exhibiting epithelial-like morphology that was isolated in 1976 from the right temporal lobe of a White, 65-year-old, male patient with glioblastoma. This cell line was deposited by N de Tribolet and can be used in neuroscience research.
ATCC SH-4; Melanoma; Human (Homo sapiens)
SH-4 is a cell line exhibiting a morphology that is a mixture of spindle-shaped and epithelial-like cells. It was isolated from the skin of a 60-year-old, White female patient with melanoma. It has applications in immuno-ocology.
ATCC Mycoplasma fermentans; control DNA
Genomic DNA isolated from Mycoplasma fermentans strain PG18 (ATCC 19989D). This whole-genome sequenced product can be used in PCR and other molecular biology applications.
ATCC Organoid Growth Kit 1D
ATCC Growth Kits are packages of recombinant proteins, small molecules and other supplements designed to make the preparation of complex media formulations for select organoid culture models easy and reliable. Kit components are supplied as powders to maximize stability and in convenient, pre-portioned, ready-to-reconstitute format that does not require aliquoting or storage once prepared.
Eurofins Discoverx KILR THP-1 Cell Pool, 2 vials. (97-1011P014)
The KILR THP-1 cell pool is a stable, engineered target cell pool, which closely reflects the heterogeneous native protein expression of tumor environments, used to measure direct cell death mediated by immunooncology treatments (e.g. checkpoint modulators, bispecifics, CAR-T, etc.) via Antibody Dependent Cell-mediated Cytotoxicity (ADCC), Complement Dependent Cytotoxicity (CDC), and Antibody Dependent Cell Phagocytosis (ADCP). This product uses EFC technology. The cell pool is a heterogeneous population of THP-1 cells that overexpress a ProLabel-tagged housekeeping gene. Upon effector cells-mediated cell lysis, ProLabel is released to the media, where EA in the detection kit produces an EFC signal proportional to the level of ProLabel released. This allows for calculation of percent lysis of the KILR cell pool. This stable cell pool is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kilr.
Amsbio LLC Color Switch, CRE report cell line: HEK293-loxP-GFP-RFP (Bsd)
Color Switch CRE report cell line: HEK293-loxP-GFP-RFP (Bsd)
Amsbio LLC HEK293-CLCN2 cell line with RFP and Blasticidin dual marker
HEK293-CLCN2 cell line with RFP and Blasticidin dual marker
Eurofins Discoverx PathHunter U2OS HRH4 β-Arrestin Cell Line, 2 vials. (93-0209C3)
The PathHunter HRH4 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. histamine) based activation of HRH4 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged HRH4 and EA-tagged β-Arrestin-2. Activation of HRH4 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC Enterococcus faecalis
Enterococcus faecalis strain NCTC 775 is a whole-genome sequenced bacterial type strain. It has applications in media testing, quality control, as reference material, as a control strain for Group D, and in water testing.
ACROBiosystems CHO/Cynomolgus Glypican-3 (GPC3) Stable Cell Line Development Service
Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
