General Cell Lines and Cell Cultures
Eurofins Discoverx PathHunter CHO-K1 SSTR3 β-Arrestin Cell Line, 2 vials. (93-0244C2)
The PathHunter SSTR3 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. somatostatin) based activation of SSTR3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged SSTR3 and EA-tagged β-Arrestin-2. Activation of SSTR3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC OKT 3; Hybridoma; Mouse (Mus musculus)
There is a Permit requirement: License form needed to be completed Material Transfer Agreement Addendum for Screening Application
The forms are available here: https://www.atcc.org/support/order-support/permits-and-restrictions
Lonza Walkersville SAEC – Human Small Airway Epithelial Cells
Lonza's Human Small Airway Epithelial Cells (SAEC) are isolated from normal human lung tissue the distal portion of the lung in the 1mm bronchiole area.Cryopreserved SAECs or Alveolar Cells are guaranteed through 15 population doublings and stain positive for cytokeratin 19.SAECs or Alveolar Cells labeled CC-2547S are suitable for air-liquid interface studies and are guaranteed for differentiation marked by cilia formation, mucin production, and TEER levels. Cells from various diseased donors are also available. Benefits:All cells test negative for mycoplasma, bacteria, yeast, and fungiHIV-1, Hepatitis B and Hepatitis C are not detected for all donors and/or cell lotsCertificate of Analysis provided for every cell lot Content:1 x Cryopreserved ampule SAEC containing ≥500,000 cells
Promocell GmbH PromoCell HDBEC-c 500,000 Human Dermal Blood Endothelial Cells, adult, cryopreserved
Primary Human Dermal Blood Endothelial Cells (HDBEC) are a subpopulation of the Human Dermal Endothelial Cells. They are isolated from the dermis of juvenile foreskin and adult skin (different locations) from a single donor.The cells are routinely analyzed by flow cytometric analysis and immunofluorescent staining: they are > 95% CD31 positive and stain positive for von Willebrand factor. In addition, they are > 90% negative for podoplanin and stain negative for smooth muscle specific alpha-actin.Blood Endothelial Cells have a key function in physiological processes like vessel tonus, capillary permeability, blood coagulation, fibrolysis, and angiogenesis. They are also useful for disease studies of atherosclerosis, tumor genesis, and thrombosis.
Eurofins Discoverx ChemiScreen CXCR6 Chemokine Receptor Stable Cell Line, 2 vials. (HTS054C)
The ChemiScreen CXCR6 Chemokine Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CXCL16) based activation of CXCR6 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CXCR6 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of CXCR6, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
American Research Products Inc AntiCD274 PD L1 B7 H1 MDX 1105
Anti-Human CD274/PD-L1/B7-H1 (MDX-1105) Research Grade
ABclonal Technology HCRTR1 Rabbit pAb
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B.
Biochain Institute Inc Paraffin Tissue Section - Human Skin Tumor: Fibrosarcoma, 5 sides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from a single human tumor. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
ATCC Staphylococcus aureus; subsp. aureus; Quantitative DNA
ATCC Genuine Nucleics can be used for assay development, verification, validation, monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load and for other molecular biology applications.
Eurofins Discoverx PathHunter U2OS HTR2A β-Arrestin Cell Line, 2 vials. (93-0401C3)
The PathHunter HTR2A cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. serotonin) based activation of HTR2A GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged HTR2A and EA-tagged β-Arrestin-2. Activation of HTR2A stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Amsbio LLC eLuCidate™ RAW 264.7, TNF-a Reporter Cell Line
eLuCidate™ RAW 264.7 TNF-a Reporter Cell Line
Genscript Corporation CHO-K1/human CD47 Stable Cell
Recombinant CHO-K1 cells stably overexpress human CD47 on the surface The surface expression of CD47 on this cell is validated by FACS analysis This cell line is recommended for cell-based binding assay to screening antibodies against CD47 or to measure binding affinity between CD47 and anti-CD47 antibodies
ATCC Quantitative Synthetic; Parvovirus B19 DNA
Quantitative Synthetic Parvovirus B19 DNA, genotype 1 can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine viral load. This preparation includes fragments from the VP1, VP2, and NS1 regions and targets genotype 1.