General Cell Lines and Cell Cultures
Eurofins Discoverx Ready-to-Assay GAL1 Galanin Receptor Frozen Cells, 2 Vials of Cells. (HTS094RTA)
The Ready-to-Assay GAL1 Galanin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. galanin) based activation of GALR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses GALR1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of GALR1, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC NCI-H2110; Lung Carcinoma; Human (Homo sapiens)
NCI-H2110 [H2110] is a cell line exhibiting epithelial-like morphology that was isolated from the lungs of a patient with non-small cell lung cancer. This product has applications in cancer research.
ATCC Escherichia coli; Quantitative DNA
Quantitative Genomic DNA from Escherichia coli strain 2002-3211 can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.
ATCC NR8383; Alveolar Macrophage; Rat (Rattus norvegicus)
NR8383 [AgC11x3A, NR8383.1] are macrophages that were isolated from the lungs of a normal rat. It has applications in immunology.
ATCC SU-DHL-1; Histiocytic Lymphoma; Human (Homo sapiens)
SU-DHL-1 is a histiocytic cell that was isolated from the lymph node of a White, 10-year-old, male patient with large cell lymphoma. This cell line was deposited by A Epstein and can be used in immunology research.
ACROBiosystems Human CCR8 2Vials
This entry represents CC chemokine receptor 8 (CCR8) which it is expressed predominantly in lymphoid tissues and has also been found in glomerular podocytes and human umbilical vein endothelial cells (HUVECs). CCR8 is associated with Th2 lymphocytes which are critical for allergy and has a role in lymphocyte activation migration proliferation and differentiation and in allergic diseases. CCR8 binds to CCL1 (also known as I-309) and to CCL16 (also known as liver expressed chemokine). It also exhibits a high affinity for three chemokines of viral origin: vMIP-I vMIP-II and vMCC-I.
STEMCELL Technologies Human Whole Peripheral Blood Collected with Sodium Heparin, Fresh, Size: 150 mL
Normal whole peripheral blood (PB) is obtained from healthy donors using Institutional Review Board (IRB)-approved consent forms and protocols. Acid citrate dextrose, solution A (ACDA), Sodium Heparin (Na-Hep), Ethylenediaminetetraacetic acid (EDTA), or Citrate-phosphate-double-dextrose (CP2D) is the anticoagulant.Certain products are only available in select territories. Please contact your local Sales representative or Product & Scientific Support at techsupport@stemcell.com for further information and to inquire about donor selection or information including BMI category, smoking status, ethnicity, etc.Browse our Frequently Asked Questions (FAQs) (https://www.stemcell.com/primary-cells-faq) on Primary Cells.
ATCC Clostridium sporogenes
Clostridium sporogenes strain SR 5 is a whole-genome sequenced bacterial strain that was isolated from a human with an acute case of gas gangrene. It is cited in USP <62> and <71> and has applications in media testing, quality control, sterility testing, and pharmaceutical and personal care.
Lonza Walkersville Hu CB CD34 Stm/Prog Cells 1M
Cord blood CD34 cells are known to contain hematopoietic stem and progenitor cells and are ideal for studies relating to transplantation and stem cells as cord blood derived cells tend to be more na ve than similar cells derived from other tissue sources High Purity and ViabilityLonza cord blood CD34 cells are isolated from cord blood mononuclear cells (MNCs) via positive immunomagnetic separation and are guaranteed to have a purity of 90% as indicated by CD34 expressing cells They are guaranteed to contain 1 million viable cells per ampoule HIV-1 and hepatitis B are not detected for all donors and/or cell lots A Certificate of Analysis is provided for each cell lot purchased Choices in Tissue Source - Cord blood CD34 cells tend to be more naive than hematopoietic stem cells from other tissue sources Thus they can be a great tool when trying to bypass HLA mismatch issues
Lonza Walkersville Rat Brain Cx-Hi-Cp Mixed Astro
Ready-to-use Clonetics Rat Brain Cortex Astrocytes are obtained from rat brain passaged once and prepared as cell suspensions for shipment on dry ice Glia are a mixture of rat cortical hippocampal and striatal astrocytes Each vial contains approximately 1 million cells Astrocytes can be easily thawed and cultured Astrocytes can be harvested and re-plated or stored frozen for later use The cells are shipped overnight Recommended medium AGM BulletKit (CC-3186)
ATCC Acinetobacter baumannii; 2208
Acinetobacter baumannii strain 2208 [81, DSM 6974] is a whole-genome sequenced bacterial type strain isolated from human urine. This strain has applications in, food testing, media testing, and quality control.
ATCC SUP-T1; Lymphoblastic Leukemia; Human (Homo sapiens)
There is a Permit requirement: License form needed to be completed Material Transfer Agreement Addendum for Screening Application
The forms are available here: https://www.atcc.org/support/order-support/permits-and-restrictions
Eurofins Discoverx ChemiScreen NPBW1 Neuropeptide B/W Receptor Stable Cell Line, 2 vials. (HTS180C)
The ChemiScreen NPBW1 Neuropeptide B/W Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. neuropeptide B/W) based activation of NPBWR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses NPBWR1 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of NPBWR1, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.