General Cell Lines and Cell Cultures
Thermo Scientific™ CellSensor™ DHFR/E2F-bla NIH3T3 Cell Line
The CellSensor™ dhfr(E2F)-bla NIH 3T3 Cell Line contains a beta-lactamase reporter gene under control of the E2F/DP1 binding sequence from the DHFR gene promoter, stably integrated into NIH 3T3 cells.
Thermo Scientific™ GeneBLAzer™ NPSR1-A-NFAT-bla CHO-K1 Cells
The GeneBLAzer™ NPSR1-A-NFAT-bla CHO-K1 cells contain the human Neuropeptide S Receptor 1-Isoform A stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ LanthaScreen™ STAT5 TF-1 Cell Line
LanthaScreen™ GFP Cellular Assays allow for the analysis of post-translational modifications for a number of target proteins in an live-cell context.
Thermo Scientific™ Tango™ RLN3R1-bla U2OS Cells
The Tango™ RLN3R1-bla U2OS cells contain the human Relaxin/Insulin-like Family Peptide Receptor 3 (RLN3R1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ RARγ-UAS-bla HEK 293T Cells
The GeneBLAzer™ RAR gamma-UAS-bla HEK 293T cells contain the ligand binding domain (LBD) of the human retinoic acid receptor gamma (RAR gamma) fused to the DNA-binding domain of GAL4, stably integrated in the GeneBLAzer™ UAS-bla HEK 293T cell line.
Thermo Scientific™ GeneBLAzer™ MR-UAS-bla HEK 293T Cells
MR-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Mineralcorticoid Receptor (MR) fused to the NA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ CellSensor™ ISRE-bla RA-1 Cell Line
The CellSensor™ ISRE-bla RA-1 Cell Line contains the beta-lactamase (bla) gene under the control of the interferon-stimulated response element (ISRE).
Thermo Scientific™ GeneBLAzer™ GR-UAS-bla HEK 293T Cells
GR-UAS-bla HEK 293T cells contain the ligandbinding domain (LBD) of the human Gluocorticoid receptor (GR) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ CellSensor™ CRE-bla Jurkat Cell Line
The CRE-bla Jurkat cell line contains a beta-lactamase reporter gene under control of a cAMP response element (CRE) stably integrated into Jurkat cells.
Thermo Scientific™ Tango™ GPR1-bla U2OS Cells
Tango™ GPR1-bla U2OS cells contain the human G protein-coupled receptor 1 (GPR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ VDR-UAS-bla HEK 293T Cells
VDR-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Vitamin D receptor (VDR) fused to the DNAbinding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ GeneBLAzer™ PPARγ-UAS-bla HEK 293H Cells
PPAR gamma-UAS-bla HEK 293H cells contain the ligand-binding domain (LBD) of the human Peroxisome Proliferator-Activated Receptor-gamma (PPAR gamma) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293H cell line.
Thermo Scientific™ GeneBLAzer™ CaSR-Gqo5-NFAT-bla CHO-K1 Cells
GeneBLAzer™ CaSR-Gqo5-NFAT-bla CHO-K1 cells contain the human calcium-sensing receptor (CaSR), (Accession No. NM_000388) stably integrated into the GeneBLAzer™ Gqo5-NFAT-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ OXTR-Gqo5-NFAT-bla CHO-K1 Cells
GeneBLAzer™ OXTR-Gqo5-NFAT-bla CHO-K1 cells contain the human Oxytocin Receptor (OXTR), stably integrated into the GeneBLAzer™ Gqo5-NFAT-bla CHO-k1 cell line.
Thermo Scientific™ CellSensor™ T-REx™ NICD CSL-bla HeLa Cell Line
This cell line is a clonal population isolated by flow cytometry. Addition of doxycycline to these cells allows for regulated NICD transcription factor expression and subsequent beta-lactamase expression.