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An intermediate in the biosynthesis of NAD+ that has been used to enhance NAD biosynthesis and glucose-stimulated insulin secretion in Nampt+/- mice and high-fat diet-induced type 2 diabetes mice
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An asymmetric phospholipid that can interdigitate with equal length (symmetric) acyl chain phospholipids in bilayer membranes to potentially minimize the hydrophobic mismatch between acyl chains
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A modified nucleoside derived from 5-methylcytosine and is a minor constituent of RNA as well as DNA for certain organisms; used in epigenetics research, especially in studies involving DNA methylation processes
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Rat type procollagen PC I ELISA Kit from CUSABIO Detection Range 62 5 pg/mL-4000pg/mL Sensitivity 15 6 pg/mL Sample serum plasma cell culture supernates Method Sandwich
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A synthetic corticosteroid; reduces BALF MMP-2 and MMP-9 activities, TNF-α levels, and neutrophil number in a mouse model of LPS-induced lung injury; prenatal administration improves neonatal lung function but decreases hippocampal and corpus callosum neuron density and induces motor function deficits in a rabbit model of late preterm birth at 0.1 mg/kg; extends gestational length in a rat model of HMGB1-induced preterm labor
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A GABAA receptor agonist whose potency varies depending on the receptor subunit composition (partial agonist at α1β2γ2 (ED50 = 143 µM), full agonist at α5 (ED50 = 28-129 µM), and super agonist at α4β3δ (ED50 = 6 µM)); acts as an antagonist at ρ1 GABAC receptors (IC50 = 25 µM).
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A benzothiadiazide that acts as a potentiator of AMPA receptors, positively modulating its response to glutamic acid (EC50 = 3.8 µM); also a negative modulator of GABAA receptors, reversibly inhibiting both evoked and spontaneous inhibitory postsynaptic currents (IC50 = 58 µM)
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A mitochondrial antioxidant; decreases transmembrane potential and production of ROS; prevents neuronal loss and synaptic damage in rat AD model; slows development of ocular pathologies; prevents acute phenoptosis following rhabdomyolysis, stroke, and myocardial infarction
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More