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A PAI-1 inhibitor (IC50 = 2.7 µM for the human enzyme); inhibits differentiation of human adipocytes at 5 µM; reduces tumor growth and microvessel density in a T24 bladder cancer mouse xenograft model at 5 and 20 mg/kg; prevents carotid artery occlusion, increases the time to occlusive thrombosis, and decreases the thrombus size in a rat model of ferric chloride-induced arterial thrombosis at 1 mg/kg
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
A class III antiarrhythmic agent; inhibits IKr in AT-1 myocytes (IC50 = 20 nM); enhances INa and increases the action potential duration in isolated guinea pig ventricular cells; decreases pinacidil-induced ventricular fibrillation in Langendorff isolated perfused rabbit hearts from 3-30 µM; increases the ERP of the left and right atrium in anesthetized pigs at 15 UG/kg, i.v.; prevents rapid pacing-induced atrial flutter in dogs from 0.25-5 mg/kg
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More