A DNA sequence encoding the Cynomolgus ITGAV (A0A2K5WCD3) (Phe31-Pro993) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the Cynomolgus ITGB6 (A0A2K5TZ36) (Gly22-Pro709) was expressed, constructed the plasmid 2. The two plasmids were co-expressed and the Cynomolgus ITGAV & ITGB6 heterodimer was purified.