Protein Interaction Antibody Pairs
Sino Biological Human ITGAV & ITGB6 Heterodimer Protein, Endotoxin-Free 100µg
A DNA sequence encoding the extracellular domain (Met 1-Val992) of human ITGAV (P06756-1) was fused with a flag tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the extracellular domain (Met1-Asn707) of human ITGB6 (P18564-1) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 2. The two plasmids were co-expressed and the human ITGAV&ITGB6 heterodimer was purified.
ABclonal Technology SKP2 Rabbit pAb
This gene encodes a member of the F-box protein family, characterized by a 40 amino acid F-box motif. F-box proteins are part of the SCF (SKP1-cullin-F-box) ubiquitin ligase complex, which is involved in phosphorylation-dependent ubiquitination. F-box proteins are classified into three types: Fbws (with WD-40 domains), Fbls (with leucine-rich repeats), and Fbxs (with various protein interaction modules). The protein encoded by this gene belongs to the Fbls class and contains an F-box and 10 tandem leucine-rich repeats. It is essential for the cyclin A-CDK2 S-phase kinase, recognizing phosphorylated CDKN1B (p27/KIP1) in S phase and interacting with SKP1. This gene is a protooncogene involved in lymphoma pathogenesis. Alternative splicing generates three transcript variants encoding different isoforms.
ABclonal Technology p-PLC gamma 2 PLCG2-Y1217
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4 5-bisphosphate to 1D-myo-inositol 1 4 5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane Mutations in this gene have been found in autoinflammation antibody deficiency and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3
Cayman Chemical MR12MIcroglobulIn Complex 20ug
Source: Recombinant human MR1 and β2-microglobulin expressed in E. coli • Amino acids: 22-292 (MR1), 21-119 (β2-microglobulin) • MW: 32 (MR1) and 12 (β2-microglobulin) kDa
ABclonal Technology p-GSK3B-Y216 - GSK3a-Y279
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily It is involved in energy metabolism neuronal cell development and body pattern formation Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease Alternatively spliced transcript variants encoding different isoforms have been found for this gene
ABclonal Technology FasLG Rabbit pAb
This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.
ABclonal Technology MAP3K11 Rabbit pAb
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.
Cayman Chemical ACSL3humnrecombIntaa 20ug
Source: Active recombinant human N-Terminal His-tagged ACSL3 expressed in E. coli • Amino acids: 45-720 • MW: 77.19 kDa
Sino Biological Recombinant Human C5AR1/C5R1/CD88 Protein (VLP, Full-Length, Flag Tag)
A DNA sequence encoding the Human C5AR1 (P21730) (Met1-Val350) was expressed with a flag tag at the N-terminus.
ABclonal Technology Phospho-eIF4EBP1-T37/T46
This gene encodes one member of a family of translation repressor proteins The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E) which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5 end of mRNAs Interaction of this protein with eIF4E inhibits complex assembly and represses translation This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling resulting in its dissociation from eIF4E and activation of mRNA translation
Sino Biological Recombinant Human AMPK Protein (full length, His Tag)
Recombinant full-length human AMPK (combination of A2/B2/G3 subunits) was expressed by baculovirus in Sf9 insect cells using C-terminal His tags.
