Protein Interaction Antibody Pairs
ABclonal Technology Phospho-MAPK14-T180/Y182+MAPK11-T180/Y182+MAPK13-T180/Y182+MAPK12-T183/Y1845 Rabbit pAb
Mapk14 (phosphoT180/Y182) monoclonal antibody is provided, clone number M139 is a monoclonal antibody prepared from mice, its clone number is M139. Mapk14 is also known as CSBP, CSPB1, Csbp1, Csbp2, Exip, Hog, MGC105413, Mxi2, Prkm14, Prkm15, RK, Sapk2A, p38, p38Hog, p38alpha, The full name of its gene is Mitogen Activated Protein Kinase 14.
ABclonal Technology HER2/ErbB2 Rabbit mAb
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases This protein has no ligand binding domain of its own and therefore cannot bind growth factors However it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported with the most common allele Ile654 Ile655 shown here Amplification and or overexpression of this gene has been reported in numerous cancers including breast and ovarian tumors Alternative splicing results in several additional transcript variants some encoding different isoforms and others that have not been fully characterized
ABclonal Technology E2F1 Rabbit pAb
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.
Cayman Chemical Cab4537-362humnrecomb 20ug
Source: Recombinant human C-terminal V5- and His-tagged Cab45 expressed in insect cells • Amino acids: 37-362 (full length) • MW: 42.38 kDa
![Genetex Inc CTLA4 Monoclonal Antibody [MSVA-152R] HistoMAX™ (GTX04439) GeneTex - IHC-Optimized Antibody.](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC3666954.jpg-250.jpg)
Genetex Inc CTLA4 Monoclonal Antibody [MSVA-152R] HistoMAX™ (GTX04439) GeneTex - IHC-Optimized Antibody.
The CTLA4 antibody [MSVA-152R] HistoMAX™ (GTX04439) is a Rabbit Monoclonal antibody in the GeneTex HistoMAX portfolio. The antibody is extensively evaluated for IHC-P using formalin-fixed human normal tissues (more than 70 different sections) and cancer tissue arrays to guarantee specificity and best-in-class performance. Information regarding both manual and autostainer staining protocols are available.Figure Legend: IHC-P analysis of human diffuse large B-cell lymphoma (DLBCL) tissue using GTX04439 CTLA4 antibody [MSVA-152R] HistoMAX. Diffuse large B cell lymphoma containing a large number of CTLA4 positive lymphocytes.
ABclonal Technology ARAF Rabbit pAb
Enables protein serine/threonine kinase activity. Involved in negative regulation of apoptotic process, regulation of TOR signaling, and regulation of cellular protein metabolic process. Predicted to be active in cytosol and mitochondrion. Biomarker of high grade glioma.
Bioss KD-Validated LDL receptor rela
LDL Receptor Related Protein 8 Primary Antibody Unconjugated Public Immunogen Range 900-963/963 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
Sino Biological Recombinant Human AMPK Protein (full length, His Tag)
Recombinant full-length human AMPK (combination of A2/B2/G3 subunits) was expressed by baculovirus in Sf9 insect cells using C-terminal His tags.
ABclonal Technology ATF2 Rabbit pAb
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cells DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene
ABclonal Technology WEE1 Rabbit mAb
This gene encodes a nuclear protein which is a tyrosine kinase belonging to the Ser Thr family of protein kinases This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2 cyclin B kinase and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase
Cusabio Technology LLC Recombinant Human Claudin-3 CLDN3 VLPs active20ug
Recombinant Human Claudin-3 CLDN3 VLPs active20ug
ABclonal Technology FasLG Rabbit pAb
This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.
ABclonal Technology ETS1 Rabbit pAb
This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.